Wu LM, Ma CA, Jain A. When Aurora B met p53: newly revealed regulatory phosphorylation in an old protein. Cell Cycle. 2011; 10 :171–2. doi: 10.4161/cc.10.2.14349. [ PubMed ] [ Cross Ref ]Wu L, Ma CA, Jain A. When Aurora B met p53: newly revealed regulatory phosphorylation ...
When does dehydration synthesis occur?What Is Dehydration Synthesis:Dehydration synthesis is the process of removing water from two molecules to form a larger molecule. One molecule loses a hydrogen atom and the other molecule loses the hydroxide ion. These ions come together and form water. Hence...
Where does oxidative phosphorylation occur? Is methane reaction anabolic or catabolic? How long are the anabolic and catabolic phases? How are anabolic and catabolic pathways similar? What is the difference between anabolic and catabolic metabolic pathways?
Many of the other Ig-domains have also been found to mediate interactions with ligands (reviewed in van der Flier and Sonnenberg2001; Zhou et al.2007) and the protein’s function are modulated by protein phosphorylation events (Murray et al.2004; Reimann et al.2017; Sequea et al.2013). L...
Does proton transport occur too, when no activating compound is bound to the UCP? We believe that this is the case with UCP1 [23]. This is much more doubtful with the other UCPs (UCP2, UCP3, avUCP). In fact, a consensus has more or less been reached considering that the new UC...
Deubiquitination is now understood to be as important as its partner ubiquitination for the maintenance of protein half-life, activity, and localization under both normal and pathological conditions. The enzymes that remove ubiquitin from target proteins
To avoid changes in apoB conformation that can occur when LDLs are adsorbed to plastic, we also screened hybridoma supernatants with a solid-phase sandwich RIA. The Fab fragment of MAb 1D1 (50 μl at 10 μg/ml in 5 mM glycine, pH 9.2) that is specific for an epitope situated ...
Aβ does not directly cause neurodegeneration The amyloid theory, which has been the mainstream explanation of AD pathogenesis, proposed originally that amyloid plaques and their major constituents, the Aβ fibrils, are the direct cause of progressive neurodegeneration in AD. However, multiple studies ...
externally imposed stress. Such is the case when there are heavy demands for secretion. Under these conditions the pool of nascent unfolded proteins may exceed the capacity of the protein folding machinery and elicit the UPR. This is reported to occur in tapetal cells during the secretion of po...
Here we discuss recent findings on how actively dividing cells cope with endogenous genomic lesions that occur frequently at repetitive, heterochromatic, and late replicating regions as byproducts of genome duplication. We discuss how such lesions, rather than being resolved immediately when they occur,...