RCTs can be designed using a superiority, equivalency, or non-inferiority hypothesis, and are usually preceded by a pilot, where the trial protocol is implemented in a small number of patients, mimicking the larger, definitive study. Even though regarded as the best available option to bring ...
Results using the benefit-risk method added further context and detail to the clinical summaries made from the trials. In the case of the SANAD II trial, the clinicians concluded that despite the primary outcome being improved by the treatment, the increase in adverse events negated the ...
To work effectively in clinical practice, a joint plan must meet the needs of potential users. So far, the needs and requirements for a medication plan, as expressed by patients and health care professionals, have not informed such plans. Co-Designing a Medication Plan There is growing ...
For another project, my colleague Lourdes Baezconde-Garbanati and I set out to design and conduct a large-scale quasi-experiment or "clinical trial" that would directly test the relative efficacy of the same health- related information presented in either a narrative or nonnarrative format. ...
We recommend that some sensitivity analysis should be the default plan in statistical or economic ana- lyses of any clinical trial. Investigators need to identify any key assumptions, variations, or methods that may impact or influence the findings, and plan to conduct some sensitivity analyses as...
Gross CPSteiner CABass EBPowe NR Pre-publication dissemination of clinical trial results: does it make a difference? Med Decis Making. 1999;19521Google Scholar 32. Soumerai SBMcLaughlin TJGurwitz JH et al. Effect of local medical opinion leaders on quality of care for acute myocardial infarction...
Although children were positive about participation and found reporting to be easy, our results invoke the need to use alternative research designs and recruitment strategies that also attract children using non-active modes of travel when evaluating AST interventions in school contexts. Trial ...
Although children were positive about participation and found reporting to be easy, our results invoke the need to use alternative research designs and recruitment strategies that also attract children using non-active modes of travel when evaluating AST interventions in school contexts. Trial ...
However, in acknowledgement of the potential for AI to support learning, the Educational Innovation Portfolio of the Office of the Deputy Vice Chancellor (Education) at The University of Sydney proactively encouraged individual coordinators to trial the use of AI within assessments. As scientists and ...
POCUS can be used as a single examination, repeated because of clin- ical need or deterioration, or used for monitoring physio- logic or pathologic changes. Interestingly, most studies that show clinical utility of POCUS were conducted within 24 h of a patient's pres- entation but not always...