Zasocitinib (TAK-279) is an oral, allosteric, highly selective, tyrosine kinase 2 (TYK2) inhibitor in late-stage clinical development for the treatment of immune-mediated inflammatory diseases, including psoriasis. Zasocitinib was developed using AI-assisted compound design strategy to create a ...
It is important to note that clinical trial results are not always conclusive, and further studies may reveal different outcomes. However, the lack of success in recent trials underscores the complexity of developing ISAC and the importance of careful selection and design of target antigens, ...
DO NOT REMOVE OR SKIP THE ISSUE TEMPLATE I understand that I will be blocked if I intentionally remove or skip any mandatory* field Checklist I'm reporting that yt-dlp is broken on a supported site I've verified that I have updated yt-dl...
The outbreaks of emerging and reemerging diseases have a high impact on the human and animal health because they are the underlying causes of disability, death, and long-term illness. For many regions those details are not, or just poorly known. Here we present on the morbidity and mortality...
Features and enhancements must be fully implemented so that they can be released at any time without additional work Automated unit and/or acceptance tests are mandatory to ensure the changes work as expected and to reduce repetitive manual worksee below!
Any information you can give us on the config will help us set up a similar environment for a recreate. Thanks. --- Comment From chavez.com 2017-06-01 18:37 EDT--- (In reply tocomment #10)> Hello, > How much RAM should we have installed in the system? Also, does this problem ...
Milliman released the results of its2025 Corporate Pension Funding Study(PFS). The study analyzes pension data for the 100 U.S. public companies with the largest defined benefit (DB) pension plans. Unlike the monthly updates provided by Milliman, this study covers the 2024 fiscal years (FY) ...
EBSTEIN ANOMALY - WHEN NOT TO TRUST THE RIGHT VENTRICLEdoi:10.1016/S0735-1097(24)04783-1Fabio Akio NishijukaFaculdade Estácio de Sá IDOMED, Rio de Janeiro, BrazilIzadora Bighetti BritoFaculdade Estácio de Sá IDOMED, Rio de Janeiro, BrazilBarbara Santos...
An approach is proposed to increase the approximation order of the method on an unstructured grid in the three-dimensional case. Computational results for load pulse propagation in a three-layer composite are presented.doi:10.1134/S0021894424030143Vasyukov, A. V.Petrov, I. B....
Description I maintain a Poetry plugin, and I got a report (mtkennerly/poetry-dynamic-versioning#198) about issues installing it with Python 3.13. It seems that changing Python versions may result in strange behavior with Poetry's intern...