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Deubiquitination is now understood to be as important as its partner ubiquitination for the maintenance of protein half-life, activity, and localization under both normal and pathological conditions. The enzymes that remove ubiquitin from target proteins
Moderation of theDeliveryeffect on pain by expectation of pain relief, controlling for desire for pain relief. In the TextDelivery(left panel), expectation has no effect (Session*Expectation p = 0.663, single contrast; the only conspicuous effects are due to baseline differences), whereas in...
and these should be considered as outcomes of leaders’ vulnerable narcissism. There are also possible boundary conditions, which go beyond the micro-level dynamics between leaders and followers that we have considered here (e.g., Hassan et al.,2023, ...
Human-AI collaborative decision-making tools are being increasingly applied in critical domains such as healthcare. However, these tools are often seen as
A test in which a series of images are taken as a patient goes through the process of having a bowel movement to assess for the presence of any structural or functional pathology. Biofeedback therapy A specialist form of physiotherapy used to treat constipation and faecal incontinence in which ...
This is due, partly, to the effectiveness of current cancer treatments: the proportion of patients who are cured (or who, at least, survive for a long time) is increasing over time. In such a context, a classical survival approach is not appropriate and cure models should be considered. ...
In the severe stages of the disease, on the other side, the clinical signs are often very obvious and easier to detect [36], but, at the same time, difficult to reverse. In these advanced stages of DED, marked by the loss of homeostasis, there is often an inherent need for the use...
The larger training volume compared to runners may be important for swimmers, since humans are evolutionarily land-based mammalians and unaccustomed to water. Additionally, due to the large distance variety, swimmers compete in multiple heats and finals during a single competition day. Here, a ...