There are currently64 biosimilarsapproved by the U.S. Food and Drug Administration (FDA). The most recent biosimilar approval wasSteqeyma(ustekinumab-stba) on December 17, 2024. What is a Biosimilar? According the to FDA, a biosimilar is a biological product that is highly similar to, and ...
Of the various drug classes, including immune checkpoint inhibitors, cytokines, toll-like receptor agonists, and oncolytic viruses, among others, several notable immune-related adverse effects were noted. They range from minor effects to more serious ones, such as renal failure, myocarditis, and ...
A biosimilar is not considered a “generic” in the same way that a traditional, small molecule drug (for example: ibuprofen or acetaminophen) is determined to be a generic. Biosimilars are "similar" because they are biologics that do not have to be exact copies of the active ingredient, as...
BRAF mutations are found to frequently occur in many cancers, and many kinase inhibitors are in clinical trials specifically targeting B-RAF kinase. Currently there is only one FDA-approved small molecule drug which targets many other oncogenes besides BRAF: Sorafenib, approved for renal cell and ...
Ensuring that public meal programs widely available tochildren, such as school lunches, offer nutritious, balanced meals is also key, she added.
Since that time, due to their unparalleled and robust response rates, six additional checkpoint inhibitor drugs have been approved by the US Food and Drug Administration (FDA) for over 50 indications in more than 15 cancer types, with response rates ranging from 10.9 to 69% [5, 6]. ...
DAD is a common manifestation of drug-induced lung injury that results from necrosis of type II pneumocytes and alveolar endothelial cells[35]. DAD is divided into an acute exudative phase and a late reparative or proliferative phase. Drugs that may cause DAD include gefitinib, an oral EGFR tyr...
Even though the Food and DrugAdministration has retracted approval of angiogenesis inhibitors in breast cancers, there may be an indication for it in the triple negative breast cancers. As bevacizumab is used in glioblastoma multiforme, there may be a need for it in CD44 high, CD24 low,...
What is a chemotherapy regimen? Can Tymlos cause bone cancer? How do Herceptin (trastuzumab) and Perjeta (pertuzumab) work together?Drug informationVyxeos Cytarabine Daunorubicin Related support groupsVyxeos (3 questions, 3 members) Cytarabine (1 questions, 8 members) Daunorubicin (1 questions,...
What is the strongest chemotherapy drug for breast cancer? Is small cell or non-small cell lung cancer worse?Which foods contain quercetin?Fruits and vegetables are the primary sources of dietary quercetin, particularly citrus fruits and onions. It is found in varying amounts in:shallots...