Given that out of the 64 codons of mRNA, 61 codify amino acids that form polypeptide chains. What are the functions of the three remaining codons? If the genetic code were overlapping, how many complete codons would the following sequence encode...
What sort of codon signals termination of translation? On a tRNA molecule, what do we call a specific sequence of three nucleotides that is complementary to a codon triplet on mRNA? There are how many different mRNA codons? a) 3 b) 12 c) 28 d) 64 e) 120 ...
Three codons on mRNA are not recognised by tRNA. What are they? What is the general term used for them? What is their significance in protein synthesis? View Solution Which one of the followings is the proper sequence in protein synthesis?
During translation, a three-nucleotide sequence of mRNA called a codon specifies whichshould be linked up next. It is important to maintain the integrity of codons so thecan link the correct amino acids together and form the correct protein. When a frameshift mutation occurs, there is an error...
What is the term given for the three nucleotide bases on a transfer RNA molecule? (a) Ribosome (b) mRNA (c) Anticodon (d) Codon. Which one is genetic material, DNA or RNA? What does DNA primase do? What is translation in regards to DNA? What is the genetic code that translates RNA...
What is degeneracy of genetic code shaala? Usually, the single amino acid is encoded by a single codon. However, some amino acids are encoded by more than one codon. e.g. Cysteine has two codons, while isoleucine hasthree codons. This is called the degeneracy of the code. ...
Low 5′ stability is considered to increase translation rates, but stem-loop topologies across the open reading frame might have variable impacts on translation. The inclusion of infrequently used codons with low tRNA abundance, or Shine-Dalgarno-like sequences [105], might affect translation rates...
Moreover, the codon optimization is essential for the mRNA stability as the codon-dependent translation elongation rate has been implicated as a major determinant of the mRNA stability [67]. Mechanistically, reduced translational elongation of mRNA with suboptimal codons results in the recruitment of ...
In cultured fibroblasts and lymphoblasts from infantile CLN1 disease patients with nonsense CLN1 mutations, PTC124, a read-through drug that promotes translation through premature stop codons, increased PPT1 enzyme activity [31], [32] and slightly affected apoptosis [31]. Kim et al. reported ...
More than 90% of proviruses in ART-treated individuals have been shown to be defective at the sequence level for replication-competent virus production due to large internal deletions, hypermutation, premature stop codons, defects in major splice donor site or packaging signal, etc. [132,146,147...