breast cancernegative lymph noderegional recurrencerisk factorsPurpose This study aimed to identify high-risk factors for regional recurrence in breast cancer patients with pathologically negative lymph nodes. Methods and Materials We retrospectively analyzed 3,800 breast cancer patients with pT1–3 stage ...
SpringerPlus 2012, 1:83 http://www.springerplus.com/content/1/1/83 a SpringerOpen Journal REVIEW Open Access Seventeen years after BRCA1: what is the BRCA mutation status of the breast cancer patients in Africa? – a systematic review Lawal AbdulRazzaq Oluwagbemiga1*, Atoyebi Oluwole1 and...
Advanced breast cancer (ABC) in young women is defined as diagnosis of ABC prior to age 40. The multitude of factors that make treating breast cancer in young women challenging in early breast cancer is further increased in the advanced setting. Current guideline recommendations are generally base...
Small nucleolar RNA host gene 15 (SNHG15) and 16 (SNHG16) are both significantly increased in PC cells [59]. The upregulation of SNHG15 is significantly associated with tumor size, lymph node metastasis, and advanced TNM stage in patients with PC. Functionally, the SNHG15 combination att...
Letrozole (Femara®) is a nonsteroidal, third-generation aromatase inhibitor administered orally once daily, which has shown efficacy in the treatment of postmenopausal women with early-stage or advanced, hormone-sensitive breast cancer.[1] Letrozole binds competitively to the heme of cytochrome P450...
Pain can be encountered in every stage of cancer until the end of life, and may interfere with the patient's treatment process, lead to treatment refusal, and substantially impair quality of life. Today, although many treatment options for cancer are available, there is s...
In a second stage, we proceeded to the reading of this initial corpus consisting of 118 texts and discarded those that were not considered pertinent to the aims of this review on “education and Chagas disease”, that is, those approached from the biomedical (epidemiological, entomological, and...
The interventions compared could be grouped into eight broad categories: radiotherapy techniques in early-stage breast cancer patients following conserving surgery; post-mastectomy radiotherapy versus no radiotherapy in breast cancer patients; the comparison of alternative radiotherapy techniques in patients with...
Comorbidity is “any distinct additional clinical entity that has existed or that may occur during the clinical course of a patient that has the index disease under study”. It is related to, but distinct from other constructs such as multimorbidity,...
Using this approach, the estimated parameter associated with the predicted ACE/ARB choice probability in the second-stage model is the LATE. We repeated this 2SLS method using ACE/ARB ATR values across the 20 different local area sizes. For each local area size, we estimated (1) the ...