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Such metatheoretical calculi can hopefully allow us to answer for ourselves: what makes a good theory, and how do we make a theory good? Acknowledgements The author would like to thank Iris van Rooij, Berna Devezer, Joshua Skewes, Sashank Varma, and Todd Wareham for organising the What ...
Background At the end of the past century there were multiple concerns regarding lack of transparency in the conduct of clinical trials as well as some ethical and scientific issues affecting the trials’ design and reporting. In 2000 ClinicalTrials.gov
When running a randomized controlled trial (RCT), a clinical site may face a situation when an eligible trial participant is to be randomized to the treatment that is not available at the site. In this case, there are two options: not to enroll the parti
Most studies do not produce their intended outcomes on time or within budget. However, it is challenging to identify the facilitators and barriers to successful study management when the “behind the scenes action” of especially digitally enabled health
Intervention to promote physician well-being, job satisfaction, and professionalism a randomized clinical trial. JAMA Intern. Med. 2014, 174, 527–533. [Google Scholar] [CrossRef] Folkman, S.; Lazarus, R.S. An Analysis of Coping in a Middle-Aged Community Sample. J. Health Soc. Behav. ...
World Medical Association Declaration of Helsinki: Ethical Principles for Medical Research Involving Human Subjects. JAMA 2013, 310, 2191–2194. [Google Scholar] Bardin, L. Análise de Conteúdo; Lisboa: Edicões, Portugal, 2011; Volume 70. [Google Scholar] Conners-Burrow, N.A.; McKelvey, ...
Coulam and her committee that it is indeed “in the best interest of all that reproductive immunology research be encouraged.” However, we owe it to ourselves, and most importantly to our patients, to perform these studies in scientifically cogent, well-designed, hypothesis-driven, clinical ...
(if any) rule should be applied in a particular circumstance. Clinical judgement incorporates science (especially the results of well-conducted research) and makes use of available tools and technologies (including guidelines and decision-support algorithms that incorporate research findings). But rather...
If we are in the presence of someone sick, who has/might have the coronavirus, it makes sense for them to wear a mask or respirator to reduce their ability to spread the disease. DIY / Homemade Masks Early on in the pandemic, the CDC announced guidance to American citizens that “cloth...