Drug use is often referred to as a steep slope, where one or two encounters can lead to dependence. In this lesson, learn about how this slope can steepen through the development of drug tolerance, which can lead to overdose and a host of other problems. Related...
(See "Obesity in adults: Drug therapy", section on 'Duration of therapy'.) Semaglutide and cardiovascular outcomes (January 2024) Semaglutide and other glucagon-like peptide 1 receptor agonists can reduce rates of adverse cardiovascular events in individuals with type 2 diabetes who have established...
Melatonin supplements still being used in the United States are in synthetic form although store owners will tell you that they are “all natural”. In the US today you can buy melatonin only as a supplement and not a drug and it can be gotten over the counter without a doctor’s prescri...
against heart attacks and strokes, we do not recommend that people with gout stop taking low-dose aspirin), certain diuretics (water pills) such as hydrochlorothiazide (Esidrix, Hydro‐D), immunosuppressants used in organ transplants such as cyclosporine (Neoral, Sandimmune) and tacrolimus (Prograf...
One opportunity for identifying a treatment option is really in the context of a companion diagnostic. Now, these companion diagnostics have an important role in the life cycle of a new drug, where health authorities, particularly the FDA often require that a new drug targeting a biomarker specif...