Gut microbial metabolite TMAO enhances platelet hyperreactivity and thrombosis risk. Cell 165, 111–124 (2016). Article CAS PubMed PubMed Central Google Scholar Butler, L. M. et al. Heterocyclic amines, meat intake, and association with colon cancer in a population-based study. Am. J. ...
Understanding the interactions between intestinal microbiota, chronic inflammation, cellular stress, and aging is essential to developing therapies aimed at reducing inflammation and slowing age-related diseases in PWH. In this review, we discuss critical knowledge gaps and highlight the therapeutic potentia...
Alzheimer’s disease (AD) is a neurodegenerative disorder that is the most common cause of dementia and currently has few clinically efficacious disease modifying therapies [1]. In order to develop disease modifying therapies, it is imperative to better understand the mechanisms of disease initiation ...
In contrast,eating more plant-proteins was linked with lower mortality and lower risk of disease.This is not the first study to find this link! In fact, eating more plant proteins is associated with lower blood pressure and cholesterol levels and makes insulin work better. In addition, substitu...
TMAO is a substance produced in the gut that can negatively impact the way the body metabolizes cholesterol, promote clotting, and contribute toatherosclerosis (plaque in the arteries). [2] “On top of that, there are already plant-based meat products now that are much lower in saturated fat...
During hibernation, changes in the bear’s gut microbiota are linked to reduced production of toxins like trimethylamine N-oxide (TMAO). As reported, free-ranging brown bears exhibit elevated choline and betaine levels during hibernation, offering protective effects. This may indicate that a ...
Good strategies depend, at least partially, on the ability of agency executives and analysts to consider, develop and implement them: that is on their practice of strategic analysis [5,6]. Meaningful strategic analysis for any organization, however, is costly, if only in terms of the ...