药理学What is pharmacology? ①药动Pharmacokinetics:what the body does to drug. Refer to the way the body handles drug absorption, distribution ,metabolism, excretion and toxicity. Onse it is determined, rational, dosage , regimens can be instituted.②药效Pharmacodynamics:what the drug does to ...
The code in this package is licensed under the MIT License.🎁 SupportThe Bioversions service was originally developed by the INDRA Lab, a part of the Laboratory of Systems Pharmacology and the Harvard Program in Therapeutic Science (HiTS) at Harvard Medical School....
What factors might be considered in determining the "safety threshold" of a drug's therapeutic index? What is pesticide resistance? Why is it that biological control is a good solution to the problem of pesticide resistance? Describe how people (or animals) develop conditioned drug tolerance. ...
Article Patsalos PN. The clinical pharmacology profile of the new antiepileptic drug perampanel: a novel noncompetitive AMPA receptor antagonist. Epilepsia. 2015;56(1):12–27. Article ArticlePubMed Man CB, Kwan P, Baum L, Yu E, Lau KM, Cheng AS, et al. Association between HLA-B*1502 al...
Pharmacology: Pharmacology is a branch of science that investigates drugs and their effects on biological systems, as well as how pharmaceuticals work in the body (also known as 'drug activities'). Examples of psychoactive drugs include alcohol, nicotine, and cannabis. ...
Translational medicine is the integrated application of innovative pharmacology tools, biomarkers, clinical methods, clinical technologies and study designs to improve disease understanding, confidence in human drug targets and increase confidence in drug candidates, understand the therapeutic index in humans,...
Safety pharmacology studiesdefined as those studies that investigate the potential undesirable pharmacodynamics effects of a substance on physiological functions in relation to exposure in the therapeutic range and above. What is Preclinical Safety Pharmacology Studies importance?
We also review the use of magnetic resonance imaging findings as an outcome measure in clinical trials assessing the efficacy of new therapeutic agents for the treatment of multiple sclerosis. More advanced applications of magnetic resonance imaging and their use in multiple sclerosis is addressed ...
As Darth Vader famously said in the originalStar Wars: A New Hope(episode IV), “Don’t be too proud of this technological terror you’ve constructed. The ability to destroy a planet, or even a whole system, is insignificant next to the power of the Force.” Our perspective and the ma...
B. et al. International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacol. Rev. 53, 527–552 (2001). This is an overview of the current knowledge of adenosine receptor biology, from gene structure to expression, distribution, biochemical properties, ...