Each parent gives one copy of the SMN1 gene to a child with SMA. A child who inherits the SMN1 gene from only one parent is unlikely to develop the condition although they may pass the gene on to their children. What are the symptoms and signs of spinal muscular atrophy? Spinal muscular...
Each parent gives one copy of the SMN1 gene to a child with SMA. A child who inherits the SMN1 gene from only one parent is unlikely to develop the condition although they may pass the gene on to their children. What are the symptoms and signs of spinal muscular atrophy? Spinal muscular...
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A good example of targeting underlying splicing mechanisms to treat diseases is with a disease calledspinal muscular atrophy, a major genetic disease of children and infants. Humans carry two near identical copies of the Survival Motor Neuron gene: SMN1 and SMN2 which are essential for the surviva...
From my initial stay, my team has initiated collaborations with two research groups at the department of biological sciences, University of Warwick, Coventry." With the laboratory of Colin Murrell, work is progressing on cloning and sequencing the sMMO gene from various methanotrophic cultures isolate...
A mutation in theSMN1gene is responsible for the majority of instances of spinal muscular atrophy (SMA). A protein necessary for proper motor neuron activity is not produced in sufficient amounts by this gene. Motor neurons perish and are, thus, unable to transmit muscular impulses. ...
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