Next-generation sequencing (NGS) is a technology for determining the sequence of DNA or RNA to study genetic variation associated with diseases or other biological phenomena. Introduced for commercial use in 200
What is the RNA complement to the sequence 5'-ACCTGGATTCG-3'? Start Codon of Translation The specific codon in the RNA strand which is responsible for the initiation of translation is known as a start codon. The universally found start codon in the case of translation is AUG, whic...
CRISPR is a technology that can be used to edit genes and, as such, will likely change the world. The essence of CRISPR is simple: it’s a way of finding a specific bit of DNA inside a cell. After that, the next step in CRISPR gene editing is usually to
Prior to RNA-Seq, the main technology for RNA analysis and gene expression profiling was microarrays. The main limitation of this technology is that it can only detect predefined RNA sequences, providing a biased view of the transcriptome. RNA-Seq is not limited to known sequences and produces...
An RNA enzyme is a strand of RNA that's able to function as an enzyme by catalyzing biochemical reactions. Though it's very rare...
What type of RNA copies the sequence of DNA bases in complimentary form? List the nitrogenous bases found in DNA and RNA. What are some fundamental discoveries in RNA biology? What are the three main types of RNA? What is the nucleotide that RNA uses instead of thymidine ("T")?
The system is made up of two key parts: aCRISPR-associated (Cas) nuclease, which binds and cuts DNA, and a guide RNA sequence (gRNA), which directs the Cas nuclease to its target. It was discovered in bacterial immune systems, where it cuts the DNA of invading viruses, called bacteriop...
Drug discovery, given its interdisciplinary nature, has always been driven by novel developments, whether in the physical sciences (such as organic synthesis) or in the biological sciences (such as the ability to sequence genomes or advances in receptor pharmacology), or, more recently, when applyi...
as molecular scissors, where a simpleexchange of the RNA guide sequence is enough to redesign the nucleasespecificity has paved the way for a revolution in the life sciences. CRISPR repeats are associated with Casproteins constituting an adaptive immune system in bacteria and archaeaprotecting them ...
We know cytosine (C) always pairs with guanine (G) in RNA but adenine (A) in DNA must pair up with uracil (U) in RNA. Base sequence in DNA strand : -TATCTACCTGGA- Base sequence in m-RNA strand : -AUAGAUGGACCU-