Role of the plasma membrane in cell signalling:The plasma membrane is the outermost layer of the living cell, and it is the living part of the cell that isolates the cell from the surrounding environment. It is a lipid bilayer with inner hydrophobic tai...
What is the role of the lysosome in a plant cell? a. What are membrane vesicles? b. How are membrane vesicles transported inside the cell? c. What is the role of SNAREs in this process? d. What is the role of COP1, COP2 and Clathrin in this process? What is the role of the "...
Multimodal interactions of drugs, natural compounds and pollutants with the gut microbiota Article 31 January 2022 References You, G. & Morris, M. E. (eds) Drug Transporters: Molecular Characterization and Role in Drug Disposition (John Wiley & Sons, 2014). Giacomini, K. M. et al. Intern...
We detected a consensus sequence for interaction with post-synaptic density-95/Discs large/Zonula occludens (PDZ) proteins (-SQF) and a tyrosine-based internalization signal (-YVNG-) in the C-terminus of EAAC1, and investigated their role in the transporter localization. We demonstrated th...
The nigrostriatal dopamine pathway that contains around 80% of dopamine in the brain and plays a role in stimulating purposeful movement. Finally, there is the tuberoinfundibular pathway that affects prolactin release.3 The neurodevelopmental disorder TS is thought to be caused by an accelerated ...
One of the earlier GWAS in PD provided unequivocal evidence regarding the role of SNCA and MAPT in PD (Table 1) (Simon-Sanchez et al., 2009). Subsequent GWAS with larger sample sizes confirmed these loci and suggested population-specific effects (IPDGC and WTCCC2, 2011, Nalls et al., 20...
[29], clathrin-mediated endocytosis [30] and caveolae/lipid-raft-mediated endocytosis [31]. Thus, Tat fulfills a role in HIV-1 pathogenesis not only as an essential protein for HIV-1 replication, but also as an extra-cellular toxin [32]. Therefore, it is relevant to develop a vaccine ...
The size of nanoparticles was found to play a critical role in both the rate and extent of cellular uptake. It was found that 50 nm transferrin-coated gold nanoparticles were taken up by mammalian cells at higher rates and extents compared to smaller and larger sizes in the range of 10–10...
What is the role of the KDEL sequence in targeting and processing proteins in the endoplasmic reticulum?Protein Destinations:Proteins are synthesized on free ribosomes in the cytosol or on endoplasmic reticulum (ER)-bound ribosomes. The default destination of proteins...
(a) Describe the structure of the vesicles. (b) Describe its function. What is the role of the lysosome in the cell? What is the function of the cytoplasm? What are vacuoles and what are their function? What is a ribosome? What are its function?