The only 4F-PCC indicated for the urgent reversal of acquired coagulation factor deficiency induced by vitamin K antagonist (VKA, eg, warfarin) therapy in adult patients with: Need for urgent surgery/invasive procedure or Acute major bleeding ...
Ever since the reversal, I have had trouble with constipation, vomiting, and a lot of pain. I have to take laxatives all the time. It is beginning to worry me, so I'm going to see another doctor and have more tests done to see if something is wrong. I wouldn't want this to ...
With the approval of the first NOAC-specific reversal agent and with others in late-stage clinical development, it is helpful to review how these agents may fit in the framework of managing NOAC-related bleeding. 展开 关键词: Anticoagulation atrial fibrillation bleeding reversal agents DOI: ...
Neuraxial anesthetic techniques are commonly used during the peripartum period to provide effective pain relief for labor and anesthesia during cesarean delivery. Major neurologic complications are rare after neuraxial anesthesia; however, spinal hematoma is associated with catastrophic neurologic outcomes (inc...
Noted shortcomings with DOACs are shorter half-lives requiring stricter adherence, lack of standardized laboratory monitoring, lack of anticoagulation reversal agents, and loss of routine coagulation monitoring leading to fewer patient-clinician interactions. This review addresses many of these limitations ...
Persistently positive antiphospholipid antibodies (aPL) in association with thromboses and/or pregnancy morbidity is the hallmark of the antiphospholipid syndrome (APS). The management of aPL-positive patients has been focused on utilizing traditional antithrombotic medications, such as heparin or warfarin....
People who take warfarin, or other anticoagulants, should consult with a physician before consuming goji berry products. Goji juice also contains a toxic alkaloid known as atropine. Its amount in the product, however, is typically well below the level considered toxic to humans. In addition to...
What to do when warfarin therapy goes too far Warfarin is certainly a lifesaver--but it can also lead to potentially fatal hypocoagulability. Here we recommend best reversal options based on the type o... P Shailendra,MR Wootten,K Nichole,... - 《Journal of Family Practice》 被引量: 13...
Noted shortcomings with DOACs are shorter half-lives requiring stricter adherence, lack of standardized laboratory monitoring, lack of anticoagulation reversal agents, and loss of routine coagulation monitoring leading to fewer patient-clinician interactions. This review addresses many of these limitations ...