Directly surrounding the airway epithelium is the sub-epithelial space, which contains mesenchymal-like cells including fibroblasts, myofibroblasts, and smooth muscle, as well as ECM that provides structural support to tissues and influences cellular behavior. Airway smooth muscle (ASM) shortening serves ...
a complete sex chromosome is the most common chromosomal aberration associated with SCAs, there are often variable karyotypes in each SCA including mosaic forms, ring chromosome (in TS), individuals who carry a higher number of X chromosomes (in KS), and other aberrations [29,43]. Whereas TS...
The study of sexual dimorphism in psychiatric and neurodevelopmental disorders is challenging due to the complex interplay of diverse biological, psychological, and social factors. Males are more susceptible to neurodevelopmental disorders including inte
Revaccination with the original series 3 mo following the intervention is recommended after hematopoietic cell transplant or CAR-T therapy.90 c Refers to efficacy in phase III clinical trials against symptomatic COVID-19 illness. All vaccines have reduced efficacy against the SARS-CoV-2 viral varian...
Survivin (also named BIRC5) is a well-known cancer therapeutic target. Since its discovery more than two decades ago, the use of survivin as a target for cancer therapeutics has remained a central goal of survivin studies in the cancer field. Many studies have provided intriguing insight into...
Lyme disease is emerging in Canada due to expansion of the range of the tick vector Ixodes scapularis from the United States. National surveillance for human Lyme disease cases began in Canada in 2009. Reported numbers of cases increased from 144 cases in 2009 to 2025 in 2017. It has been ...
Perceptions of system competence and communicative ability, termed partner models, play a signifcant role in speech interface interaction. Yet we do not know what the core dimensions of this concept are. Taking a psycholexical approach, our paper is the frst to identify the key dimensions that ...
Measuring the Earth’s Global Average Temperature is a Scientific and Objective Process El Niño and Climate Change Climate Models have Accurately Predicted 30 Years of Warming A Climate Tipping Point Will Happen at 1.5°C of Warming Weather Climate Change Will Increase the Number and Severity of...
(CSF) barrier and/or the endothelial cells of the BBB, or via the inflammatory cells of the cytokine storm as “trojan horses” to attain access into the CNS, where the virus is transferred intracellularly and is concealed by the host immune cells [6]. One study supported the hematogenous-...
“immunogenicity of low molecular weight organic chemicals is dependent on modification of self-proteins,” evolved from Landsteiner and Jacob’s discovery of a correlation between the reactivity of dinitro-halogenated benzenes and their sensitization potential. The hypothesis rapidly evolved to encompass ...