Original research in cardiac magnetic resonance (CMR) is growing most explosively, and the editors of the JACC family of journals have had a front row seat to some of the best papers in this area. We felt it might be useful to bring together our favorite original research papers from variou...
The frontal lobeis the area responsible for personality and movement. The pre-frontal portion is perhaps the most evolved part of the brain and specifically allows judgment, planning and organization, problem-solving, and critical thinking. This is the area that gives us the ability to feel emoti...
Amyloidosis is a rare disorder that occurs whenamyloid proteinsbuild up in organs and tissues. This protein build-up makes the organs not work properly. The affected organs may include the heart, kidneys, liver, spleen, nervous system, and digestive tract. The signs and symptoms of amyloidosis ...
Cardiac biopsiescardiomyocytescaveolin-3immunoglobulin light chainslight chain (AL) cardiac amyloidosishigh resolution confocal microscopyDAMAGECELLSBackgroundCardiac involvement in systemic light chain amyloidosis (AL) leads to chronic heart failure and is a major prognosis factor. Severe cellular defects are ...
Light chain (AL) amyloidosis is archetypical of a plasma cell dyscrasia causing organ dysfunction through deposition of its monoclonal protein. When identified at an early stage, much or all of the organ dysfunction may be reversible with treatment of the clonal entity; however, the sequelae of...
A family history of cardiomyopathy, heart failure, or sudden cardiac arrest Connective tissue disease and other types of autoimmune disease Coronary artery disease or a heart attack Diseases that can damage the heart, such as hemochromatosis,sarcoidosis, oramyloidosis ...
What is a BNP?Heart Failure:Heart failure occurs when the heart is not pumping blood as effectively as it should. This causes the cardiac muscle to become overworked and enlarged.Answer and Explanation: BNP stands for brain natriuretic peptide, although it has nothing to do with the brain and...
4.6. Cardiac Amyloidosis Cardiac amyloidosis, characterized by extracellular amyloid fibrils in the heart, is predominantly seen in men, who make up 90% of patients with wild-type transthyretin cardiac amyloidosis (ATTRwt) [82]. Sex hormones may influence this condition, as animal models show that...
Determining a patient’s LVEF is essential in terms of diagnosis, treatment, and prognosis. Specifically, while levels of NT-proBNP are typically elevated among patients with HFrEF, they are often in the normal range among patients with HFpEF, thus making the diagnosis of these latter patients ...
Poor Prognosis: Restrictive Cardiomyopathy: Both asymptomatic cats and those showing illness in study Cardiomyopathy UK chief, Joel Rose said:"We're so grateful that Neil is running the London marathon in aid of Cardiomyopathy this year - and for all the amazing fundraising the Ferriers' have don...