Biology of Sex Differences 2012, 3:24 http://www.bsd-journal.com/content/3/1/24 REVIEW Open Access Sex and gonadal hormones in mouse models of Alzheimer's disease: what is relevant to the human condition? Dena B Dubal*, Lauren Broestl and Kurtresha Worden Abstract Biologic sex and ...
Alzheimer’s disease, the most common neurodegenerative condition, is reaching epidemic proportions. In the absence of effective interventions, over 50 million people worldwide will suffer from this devastating dementia by the year 2050 [2]. The symptoms of AD begin insidiously with memory impairment ...
This is the opening paper in the special issue of Fungal Diversity, which collates the data on defining species. Defining and recognizing species has long
The narrative identity framework is a useful framework to understand teachers’ experiences and their resulting reflection. Narrative Identity Theory (McAdams,Citation2001; McAdams & McLean,Citation2013) suggests that individuals develop, internalise and make meaning of their evolving self-stories, which pr...
The hunt for pathogenic mitochondrial DNA (mtDNA) mutations is often fueled by the seeming novelty of mutations that are either nonsynonymous or affect the protein synthesis machinery in patients. In order to determine the novelty of a detected mutation, the working geneticist nearly always consults...
Pain can be encountered throughout every step of cancer treatment, and thus all practicing oncologists must be capable of assessing pain, know the possible underlying pathophysiology, and manage it appropriately. The purpose of this review is to discuss neuropathic pain and NCP...
Ga-PSMA-PET/MRI – What is the value of quantitative data from multiparametric MRI alone or in conjunction with clinical information? Author links open overlay panelStephan M Skawran a b c, Vanessa Sanchez a c, Soleen Ghafoor a c d, Andreas M Hötker a c, Irene A Burger b c e, ...
Your life is organized like an orbit. I know. 了解了这点,就知道为何四年于相隔千里的我们,似乎只是弹指一挥间而已。 我其实了解小女儿的心理,是希望多一点surprise多一点romantic多一点傻里吧唧的指天划地的。可惜我这方面的才能似乎多用在0,1组成的无机世界里了,于是只能委屈她了。大多数的时间,她就一...
is low and P removal exceeds average inputs of 2 kg P/ha/year, the resulting nutrient depletion severely restricts yields (e.g., maize yields < 1,000 kg/ha/year) and accelerates soil degradation. In other regions, excessive P inputs produce economic inefficiencies and increase the risk of...
to oppose.1 In place of the idea that causality is a form of necessitation,2 Anscombe offers us a view that is, in her own estimation, "so obvious as to seem trite", being based on the simple idea that effects "derive from, arise out of, come of, come of" their causes (136)....