“The brain in love finds the nucleus accumbens (a major reward center) linked to the frontal cortex to generate positive feelings, and has a reduced connection to the amygdala (the fear center). “Those connections reverse in the process of falling out of love. An individual finds the relat...
and I was hooked. I just couldn’t get enough of it. (Pardon the word choice.) Bottom line, brain science is tremendously exciting, highly logical, constantly evolving and surprisingly easy to understand. And for that reason, it can be seductive, giving us a sense...
alter the release of dopamine in a brain region called the nucleus accumbens. This area is part of the brain’s reward pathway, which is sensitive to experiences that give us pleasure and drives us to repeatedly seek them out. The reward pathway is essential to our well-being— but addictiv...
Conclusions: DBS is a promising tool in the treatment of refractory OCD patients. The existing data show that the nucleus accumbens and the anterior limb of the internal capsule are the most promising targets for this treatment. Furthermore, DBS has shown new and interesting perspectives in the ...
The Direct and Indirect Pathways of the Nucleus Accumbens are not What You ThinkNeuropsychopharmacology, the official publication of the American College of Neuropsychopharmacology, publishing the highest quality original research and advancing our understanding of the brain and behavior....
Hoebel. “Food Reward and Cocaine Increase Extracellular Dopamine in the Nucleus Accumbens as Measured by Microdialysis.” Life Sciences, vol. 42, no. 18, Jan. 1988, pp. 1705–12. Accessed 4 Nov. 2020. “Injections of amphetamine or cocaine increased extracellular dopamine five-fold.” [10]...
Drugs of abuse increase extracellular dopamine levels in the nucleus accumbens, a brain region that is involved in re- ward and reinforcement neurocircuitry. Activation of GABA-B re- ceptors in the nucleus accumbens reduces firing of dopaminergic cells and inhibits the release of dopamine, thus it...
Users show brain volume reductions in the nucleus accumbens in both the shell (39%) and the core (42%) [14]. Reduced functional connectivity in the nucleus accumbens accurately predicts depression in 74.7% of users [15]. Cognitive Impairments And Memory Loss ...
Whether you’re listening to the driving beat of a Daft Punk song or the opening chords of a mellow Jack Johnson track, both have an effect on your brain that is not seen in any other animal. When you listen to music, a part of your brain called the nucleus accumbens activates. This...
Other MERFISH studies of neuron types in hypothalamus or nucleus accumbens also reveal strong correlation between transcriptomic specificity and anatomical/subregional specificity (Chen et al., 2021; Moffitt et al., 2018). Download: Download high-res image (1MB) Download: Download full-size image ...