Abnormal tumor microenvironment and immune escape in multiple myeloma (MM) are associated with regulatory T cells (Tregs), which play an important role in maintaining self-tolerance and regulating the overall immune response to infection or tumor cells.
What are the effects of drugs on Treg cells in multiple myeloma, and what are the applications of treg cells in therapy? Introduction Multiple myeloma (MM) is the most common form of plasma cell malignancy, accounting for about 1.7% of all malignant tumors [1]. Although the use of a vari...
Extracorporeal photopheresis (ECP) is an FDA-approved immunotherapy for cutaneous T-cell lymphoma, which can provide a complete response in some patients. However, it is still being determined who will respond well, and predictive biomarkers are urgently
It is in the acute phase of infection that activated effector T cells are selected, as are future memory T cells [2]. The latter cells in a certain amount persist in the body for decades, ready to mediate an enhanced and accelerated response to reinfection. Furthermore, aside from being ...
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