The glomerular filtration rate (GFR) is a measure of how well your kidneys are removing waste from your blood, which can be determined using an estimated GFR (eGFR) test. The test gets its name from glomeruli -- the parts of your kidney that filter out waste. (Photo credit: Image Source...
Metabolic reprogramming is a pivotal biological process in which cellular metabolic patterns change to meet the energy demands of increased cell growth and proliferation. In this review, we explore metabolic reprogramming and its impact on fibrotic disea
What is a Nephrologist (Kidney Doctor)? Share: A nephrologist, also known as a kidney doctor, is a kidney disease specialist and is the most qualified doctor to help you manage your kidney health. If you’re living withchronic kidney disease(CKD), a nephrologist offers the expertise, guidanc...
Immunomodulatory drugs (IMiDs) have become an integral part of therapy for both newly diagnosed and relapsed/refractory multiple myeloma (RRMM). IMiDs bind
For therapeutic care of advanced-stage NS-NSCLC at diagnosis it is recommended to evaluate the status of at least five genomic biomarkers (the “big five”: epidermal growth factor receptor (EGFR), anaplastic lymphoma kinase (ALK), v-ros avian UR2 sarcoma virus oncogene homolog 1 (ROS1), ...
Small-cell lung cancer (SCLC) is a deadly tumour accounting for approximately 15% of lung cancers and is pathologically, molecularly, biologically and clinically very different from other lung cancers. While the majority of tumours express a neuroendocrine programme (integrating neural and endocrine pro...
The existence of a cancerous lesion can sometimes be detected through the analysis of the altered behaviour of cells that are located substantial distances away from the primary lesion, a phenomenon that is known as the 'field effect'. Partial wave spectroscopy takes advantage of the field effect...
Like the little Bo Tangbrewerypapermill of today’s story, found in China. Somehow the Lawrence Berkeley National Laboratory in California is involved. Oh what Botangled web we weave By Smut Clyde I am not absolutely certain that “Tripartite motif 16 inhibits hepatocellular carcinoma cell migration...
Today’s trials are much more likely to focus on patients who have been selected to have the greatest odds of responding to the new therapy. That may seem obvious now, but it’s important to appreciate what a big change that is from the early 2000s, when the EGFR inhibitor Tarceva got...
Remdesivir is an antiviral medication used to treat coronavirus disease (COVID-19). Do not co-administer with chloroquine or hydroxychloroquine; may reduce remdesivir’s antiviral activity. Common side effects of remdesivir include decrease in estimated glomerular filtration rate (eGFR), decrease in cre...