The phytosynthesized TiO2 NPs with an average size of 34nm displayed exceptional antimicrobial and cytotoxic activities, as demonstrated by MTT and NUR assessments of SaOS-2cell lines, with IC50 values of 80.6
Mebendazole is a broad-spectrum anthelmintic that is active against both larval and adult stages of nematodes selectively binding the β-subunit of tubulin, thereby inhibiting intestinal microtubule synthesis in the parasite (IC50 = 0.19 µM for Giardia in vitro). As a tubulin-binding agent, mebe...
Escin IA is a triterpene saponin isolated from horse chestnut, which inhibits HIV-1 protease with IC50 values of 35 μM. Escin IA has anti-TNBC metastasis activity, and its action mechanisms involved inhibition of epithelial-mesenchymal transition process by down-regulating LOXL2 expression. To s...
What is IC50 in biochemistry? What is abs basophils? What is the clade Testudines? What is Kw in biochemistry? Define biotechnology What is a suicide plasmid? What is systole? What are basophils? What is osmosis? What is overharvesting?
Today it is well established that these isoforms, COX1 and COX2, exist and are encoded by separate genes on different chromosomes. Cyclooxygenase inhibition formed the basis for the success of non-steroidal anti-inflammatory drugs (NSAIDs) in treating a variety of pain syndromes. The drawback,...
What is chemical neuroscience? What is molecular biophysics? What is a biochemical? What is analytical biochemistry? What is chemical pathology? What is shedding neurology? What is IC50 in biochemistry? What is organismal biology? What is spermatogenesis?
Apremilast is a small molecule inhibitor of PDE4, an enzyme that breaks down cyclic adenosine monophosphate (cAMP). Pharmacodynamic mechanism: In inflammatory cells, PDE4 is the main enzyme responsible for this reaction. The resulting increase in cAMP levels downregulates the expression of many pro-...
Advanced disease is associated with meta- stases to distant sites, including the lung and bone. Before the advent of targeted therapies, the prognosis for advanced GISTs was poor owing to their inherent resistance to both chemotherapy and radiation therapy. During the past decade, GISTs have ...
Covid -- What We Know Now by David Archibald 22 December 2022 This is a boring article about why Trump didn’t fire Fauci, but it reminds us of one interesting fact. The National Institute of Allergy and Infectious Diseases (NIAID), which coordinated a
Technical cleanliness is an analytical standard to determine the level of particulate contamination on machined parts. The goal of technical cleanliness is to characterize the particles on the components and to ensure that particles below a certain defin