The article examines the link between Paget's disease of bone (PDB) and hyperparathyroidism (HPT). Management of patients with PDB and HPT should include a routine evaluation of the calcium/phosphate/parathyroid axis. Once the link is recognized, the indication for parathyroidectom...
Variation in the HPT axis thus might allow for enhanced matching of novel environments by adjusting timing of major life history events. Finally, in the shorter term scale of a range expansion front, recent work has suggested that epigenetic mechanisms may serve to generate additional phenotypic ...
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1. Introduction Parvalbumin (PA) is a small, acidic, mostly cytosolic Ca2+-binding protein of the EF-hand superfamily. It was found in lower and higher vertebrates, including humans (for reviews, see [1–4]). PA was found in fast twitch muscle cells, heart tissue, nephrons, specific ...
The functional activity is revealed by a flow of physiologically relevant inorganic ions, such as Na+, K+ and Cl−, across the BLM either from cyclic voltammetry (current-voltage curves in biophysical jargon) or chronoamperometry measurements (current-time curves) [3]. A major drawback of ...