At each step, we further limit the type of expanded systems to fit the known microbiology until a detailed description of the system is obtained. This methodology produces mathematical descriptions of the required biological systems that are more robust to changes in the precise function and rate ...
Cav3 is the least-homologous subfamily of Cav channels, displaying only an ∼25% amino acid sequence identity with the Cav1 and Cav2 subfamilies. Differences in sequence are translated to differences in structure and function, with Cav3 channels activating and inactivating at significantly lower ...