Semustine is a nitrosourea class of cell cycle non-specific antitumor drug. It is most sensitive to cells at the G1/S boundary or early S phase, and also has inhibitory effects on G2 phase cells. After entering the body, the molecule of Semustine can be broken into two parts. One p...
Chlorogenic acid is condensed from the carboxyl group of caffeic acid and the hydroxyl group of quinic acid to depsilic acid. It is a phenylpropanoid substance synthesized by plant cells through the shikimic acid pathway. There are esters in its molecular structure bonds, unsaturated double bonds, ...
However, the effect would not be due to a pharmacological action attributed to the chemical composition of the medicine.In one survey, only 3% of U.S. physicians reported using actual sugar pills as placebos, but 41% said they had used over-the-counter painkillers and 38 percent said they...
Although target-based drug discovery is currently the dominant approach to drug discovery and development, the latest comprehensive assessment shows that its results are not as good as they could be. The number of drugs discovered by this approach is relatively small, and their therapeutic effects r...
Anything, such as a substance, emotion, or action, to which one is addicted. Medicine Any treatment or cure. A legislative remedy might be some harsh medicine; is that cure worse than the ill? Drug Any commodity that lies on hand, or is not salable; an article of slow sale, or in ...
What is onset of action of a drug? the point at which the activity of a drug is apparent, generally measured in terms of the time elapsed between administration and the appearance of its pharmacological effects. How do nurses use pharmacodynamics?
The latest advances in asthma treatment have highlighted the significance of eosinophilia and the possible role of some pro-eosinophilic mediators, like in
(WL) and weight maintenance remains a challenge, as 80% of WL is expected to be regained over the next 5 years [4,5]. The main drivers for weight regain after significant WL include the persistence of a lower resting metabolic rate and the increased appetite, possibly mediated through long...
is mainly reflected in its regulation of the human immune system. It can stimulate the human immune system, enhance human resistance, and effectively prevent and treat various diseases. In addition, Polydatin also has a variety of pharmacological effects such as liver preservation and anti -tumor,...
In addition, continuous improvement in the understanding of PD disease mechanisms resulted in the identification of new pharmacological targets. Applying novel trial designs, targeting of pre-symptomatic disease stages, and the acknowledgment of PD heterogeneity raise hopes to overcome past failures in ...