Third, this review revisits outmoded dogmas about the basic science of type 2 diabetes—premises that continue to be widely reiterated in physician education but are, in fact, incorrect. Today’s type 2 diabetes
Dyslipidemia is when the blood test indicates high total cholesterol, high LDL bad cholesterol, low HDL good cholesterol, or high levels of triglycerides. A broader definition could include elevated levels of other fatty materials or even too-low levels cholesterol and triglycerides, but as a ...
An outstanding challenge is to identify which NAFLD patients have NASH, and so are at risk of cirrhosis. Another challenge arises from the association of NAFLD (and particularly NASH) with insulin resistance, impaired glucose tolerance or type 2 diabetes, atherogenic dyslipidemia, and metabolic ...
The planning of a clinical trial depends on the question that the investigator is addressing. The general objective is usually obvious, but the specific question to be answered by the trial is often not stated well. Stating the question clearly and in ad
Regardless of the role of dyslipidemia in renal disease, its treatment has become a mandatory goal in the attempt to reduce the risk of ASCVD in patients with CKD. Despite dyslipidemia in CKD is predominantly characterized by the accumulation of triglyceride-rich lipoproteins (TRLs), all guidelines...
Despite this relatively simplistic definition, it is a chronic disease, a major public health problem that adversely effects all aspects of mental and physical health. Obesity has a growing worldwide prevalence irrespective of age, sex, race, or socioeconomic status [2]. Nearly a third of the ...
On the basis of these data, practice guidelines in Canada, Europe, and the United States have made strong recommendations regarding the diagnosis and management of dyslipidemia. Herein, we review the recent data that shows a causal link of ApoB lipoproteins with ASCVD; we outline the mounting ...
Progression to repair site occlusion was uncommon (<1%); but importantly, the development of a high-grade restenosis after CEA was associated with an increased risk of ipsilateral stroke [8]. Female sex, diabetes, and dyslipidemia were independent predictors of restenosis or occlusion after the ...
Diabetes mellitus (DM) is becoming increasingly prevalent worldwide. Although major complications of this condition involve kidney, retina and peripheral nerves, the skin of diabetic patients is also frequently injured. Hence, interest is mounting in the definition of the structural and molecular profile...
Cardiometabolic diseases (CMD), including type 2 diabetes (T2D) and cardiovascular disease (CVD), and their associated factors, such as hypertension, dyslipidemia, insulin resistance and obesity are among the leading causes of morbidity and mortality in both sexes [1]. However, men and women exper...