Targeted drug therapies are often the first-line treatment – that is, the first approach your doctor will try – for advanced or symptomatic CLL. People who relapse might get targeted therapy, too. These medic
TLS is caused by the fast breakdown of cancer cells. TLS can cause kidney failure and the need for dialysis treatment, abnormal heart rhythm, seizure, and sometimes death. Your healthcare provider may do blood tests to check you for TLS. The most common side effects of IMBRUVICA® in adul...
CLL is a?chronic disease; therefore, a?proportion of patients will require multiple lines of therapy. In this review, we present the current treatment options for patients with CLL and discuss potential optimal treatment combinations.doi:10.1007/s12254-021-00776-4Daniel,Heintel...
Clinical trials are a type of research that has people as the subjects. They're the main way researchers can tell if a new treatment – be it a medical device, a drug, a diet, a behavior, or any other remedy – works and is safe for the general public to use. Often a clinical tr...
B-Cell Lymphoma Treatment The type of treatment you get depends on your overall health, the type of lymphoma you have, and whether it has spread. You might get one treatment or a combination. Your doctor will help you find the treatment strategy that is right for you. ...
Survival analysis is one of the main tools for evaluating the burden of a lethal disease, as it examines the elapsed time from a starting time point (e.g. diagnosis, start of first-line treatment) until death [1]. However, it is common that not all deaths occurring in the patient cohor...
In the current system of radiological protection, risk to a specific organ or tissue is considered to depend on the absorbed energy averaged over the target mass exposed. The biological outcome of the exposure is determined not only by the total absorbed dose but also by the time frame of the...
Survivin (also named BIRC5) is a well-known cancer therapeutic target. Since its discovery more than two decades ago, the use of survivin as a target for cancer therapeutics has remained a central goal of survivin studies in the cancer field. Many studie
Although several genes and pathways have been found to participate in the occurrence and progression of PC, the underlying mechanisms are still unclear. Therefore, it is extremely important to investigate novel and effective regulatory models for the further treatment of PC [8]. Long noncoding RNAs...
Campath 1H is the brand name of a monoclonal antibody known as alemtuzumab. This drug is used in treatment of B cell chronic lymphocytic leukemia (B-CLL) and is being investigated in other leukemias, rheumatoid arthritis, multiple myeloma and several other diseases including multiple sclerosis. It...