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Since at least the mid-1980s we have lived in a world of shareholder primacy.2 In this world the primary duty of directors is to maximize the value of the corporation for the benefit of the stockholders. Directors who reject this notion, who take actions that are for the primary benefit ...
However, this is exactly the idea that has been driving Wierzbicka’sworksince the 1970s.Natural semantic (legal?) metalanguage175 Wierzbicka took the“golden dream”of XVII century rationalist philosophersas a starting point for modern linguistic research. In her 1972 book,SemanticPrimitives,she ...
We will focus our attention on the role of B/A-BAs, as they are the most important ones in the gastrointestinal context. Another important BA for the central nervous system (CNS), the gamma-aminobutyric acid (GABA), is derived from the amino acid L-glutamate. Many other BAs, outside ...
The HH ligand is bound by a large multipass transmembrane protein called Patched (PTC). In the absence of HH, PTC inhibits the signalling activity of the seven-pass transmembrane protein Smoothened (SMO); however, once PTC has bound HH, this inhibition is relieved and SMO can trigger an ...