This leads to ischemia and eventually death of cardiomyocytes [2]. The location and duration of the occlusion is determinant for the outcome. However, during the last decades, more patients enter the wound-heal
Legs:Doctors call this “critical limb ischemia.” It’s a severe condition you can get withperipheral artery disease(PAD). That’s a condition where you have plaque build-up in the arteries of your leg. It causes intensepain, even when you’re resting. If it’s not treated, you could...
Acute ischemia is a serious condition and needs immediate medical treatment. One must seek immediate medical assistance if he or she is experiencing pain or pressure in the chest, breathing problems, severe headache, pain in the abdomen, confusion, loss of consciousness, sudden problems with memory...
Geelkerken RH, Huisman AB, Kolkman JJ: What is the best diagnostic approach for chronic gastrointestinal ischemia - JA () Citation Context ...capnograph, and allows for semicontinuous measurement. An abnormal tonometry test after exercise or test meals allowed for accurate selection of patients ...
What is the best treatment for stroke? Emergency IV medication. An IV injection of recombinant tissue plasminogen activator (tPA) — also called alteplase (Activase)— is the gold standard treatment for ischemic stroke. An injection of tPA is usually given through a vein in the arm with the ...
What are the implications of sex differences in cell death for treatment after neonatal hypoxia-ischemia, if any? doi:10.1038/s41390-025-04134-6Nature Publishing GroupPediatric ResearchMcDouall, AliceDepartment of Physiology, The University of Auckland, Auckland, New ZealandWood, Thomas R.Department...
Systemic inflammation is precipitated by the surgical trauma and contact of the blood components with the ECC circuit, which causes hemolysis, endotoxemia and ischemia due to by the clamping of the aorta.36 In brain tissue, inflammation is associated with a reduction in the self-regulation of ...
Potential drug–drug interactions mediated by the ATP-binding cassette (ABC) transporter and solute carrier (SLC) transporter families are of clinical and regulatory concern. However, the endogenous functions of these drug transporters are not well understood. Discussed here is evidence for the roles ...
Conclusions: Accurate recognition and differentiation of penetrating ulcers from classic aortic dissection at initial presentation is critical for optimal treatment of these patients. For penetrating ulcer, the prognosis may be more serious than with classic type A or B aortic dissection. Surgical ...
This paper examines work that has been done so far to characterize various aspects of cell death in the retinal ischemia model, such as various pathways which are activated, and the role neurotrophic factors, and discusses how these are relevant to the treatment of ischemic damage in both the ...