Is telomerase a DNA polymerase? What is a promoter in DNA replication? What is the difference between PCR and DNA sequencing? How many DNA polymerase are in eukaryotes? Is DNA polymerase 1 used in the leading strand? The DNA replication enzyme that most closely resembles RNA polymerase is: a...
Perhaps the most common form of transcriptional regulation is the binding of certain transcription regulators, known as promoters. These promoters bind to respective promoter sequences in order to express transcription and upregulate protein production....
Typically, the strand running 5′→3′ from the interior to the chromosome end is rich in G-residues and is extended to form a Genetic factors and telomerase activity Soon after its discovery in Tetrahymena, telomerase activity was detected in other ciliated protozoa 13., 14., as well as ...
The continuous advancements in cancer research have contributed to the overwhelming evidence of the presence of telomerase in primary and secondary tumours
The situation became more complicated when it was found that telomerase activity is present in stem cells and dividing transit cells of renewing tissues, and even when cell division is induced in ti...Artandi, S.E. & DePinho, R.A. (2000). Mice without telomerase: what can they teach ...
J. et al. Mutations in the reverse transcriptase component of telomerase (TERT) in patients with bone marrow failure. Blood Cells Mol. Dis. 34, 257–263 (2005). CAS PubMed Google Scholar Vulliamy, T. et al. The RNA component of telomerase is mutated in autosomal dominant dyskeratosis ...
The absence of telomerase in somatic tissues is thought to promote genome instability at initial stages of oncogenesis, favoring the emergence of cancer-associated chromosomal abnormalities; restablishment of telomerase activity is expected afterwards if long term cell cycling is to occur. In addition ...
aThe authors reported 62% sensitivity and 96% specificity for telomerase activity in exfoliated urothelial cells 作者在被剥落的urothelial细胞报告了62%敏感性和96%特异性为telomerase活动[translate] aОнавыходитзамужзаизвестногохоккеистаСергеяГурин...
a虽然在处理工业废气中NOx时,通常使用氨为还原剂,但是在氨的使用中有许多缺陷 Although in processing industry waste gas time NOx, usually uses the ammonia is the reducing agent, but has many flaws in the ammonia use[translate] aразработанногоподрядчиком, согл...
is proportional to the concentration and action time. That is, the greater the concentration, the longer the action time, and the more apoptotic cells. In short, pine needle oil can cause MCF7 cell loss, apoptosis and autophagy, which may be related to the reduction of telomerase activity ...