What is a G-spot? Let’s start at the beginning – what even is a G-spot? The G-spot is an internal erogenous zone that can be found just inside the vagina, at the front of the vaginal wall. This spot is made up of sensitive tissue that, like the clitoris, can feel amazing whe...
The clitoris is made of erectile tissue and enlarges when aroused just like a penis does. Because it’s internal, women are not conscious of their clitoral erections. "Seeing the clitoris in its entirety helps a woman understand how her pleasure can build," White adds. "Because it’s made...
If a doctor suspects that a patient has a condition which is related to target cells of particular concern, tests may be ordered to determine whether or not they are present. Blood and tissue samples can both be analyzed for the presence of target cells to gather information which could be ...
What is the main need that human tissue research addresses?Despite all our advances and improvements in science, there is still a problem with translation from pre-clinical to clinical — in particular, our prediction of efficacy. Human tissue testing can validate that a drug target will benefit...
Mertens, What is important to target fibrosis: location, location, loca- tion! Of cold-shock proteins,... M Pabst,PR Mertens - 《International Urology & Nephrology》 被引量: 4发表: 2011年 Bacterial cold-shock proteins Members of a family of small cold-shock proteins (CSPs) are induced ...
Regardless of its pathogenesis, the main aspect of organ fibrosis is excessive extracellular interstitial collagen deposition. The tissue cicatrization eventually results in loss of function. The highlighted article by Higashi et al. describes that taking a long visionary way may eventually succeed, ...
[21]. Yin H, Li L, Feng X, et al. 2D4, a humanized monoclonal antibody targeting CD132, is a promising treatment for systemic lupus erythematosus. Signal Transduct Target Ther. 2024;9(1):323. [22]. Wang L, Yin H, Jiang J, ...
Table 1. Off-target effects of TTCC blockers. ConcentrationReported effectCell/tissue typeRefs Mibefradil 10 µM Inhibits volume-activated Cl− channels Pulmonary artery endothelial cells 176 10 µM Inhibits Ca2+-activated Cl− channels 3.4 µM (IC50) Blocks L-type channels Spinal motoneur...
and size of the PCR product can be significantly affected by characteristics of the sample itself and the method chosen for nucleic acid extraction and purification. Ideal methods will vary depending on the source or tissue type, how the sample was obtained ...
Method for the production of a cell and/or tissue and/or disease phase specific medicament What follows is a design of active specific DNAzymes and siRNA which bind to the target sequence and cleave it such that a medicament against chronic inflammatory diseases and autoimmune diseases is provided...