Clearance from systemic circulation = [rate of elimination] / [concentration].Maintenance dose = [desired plasma concentration at steady state] x [clearance] / [bioavaliability of the drug].NOTE: Medications obeying first-order kinetics reach steady-state concentration in 4-5 half-lives....
) gradually replaced the widespread clinical application of Sodium nitroprusside dihydrate. The reason: either because they have a better effect on arteries. Strong selectivity, either because they have fewer side effects. However, despite these risks, Sodium nitroprusside dihydrate is still used in ...
Stimulation of cholinergic receptors mediates cerebral vasodilation, increased systemic perfusion pressures, and elevated intracranial pressure. Cholinergic stimulation is also responsible for increased salivary and bronchial gland secretions. Contraindications And Precautions Ketamine is contraindicated in patients ...
28 This is also confirmed by looking at reports of adverse reactions to placebo where more than 35% of the participants in the placebo arms have reported systemic adverse reactions.29 Furthermore, reports have indicated that among previously reported severe allergic reactions, up to 50% were non...
Chlorhexidine mouthwash is the near-neutral solution (pH range 5-7), only advised for topical use and never for systemic administration.
(4)Which of the following is the best way of studying pharmacology for medical students and practitioners?___ A. to have a broad botanical knowledge B. to select a plant and its preparation C. to have the ability to purify natural plants D. to have curiosity that stimulates them to learn...
Thyss A , Suciu S , Bertrand Y . et al. Systemic effect of intrathecal methotrexate during the initial phase of treatment of childhood acute lymphoblastic leukemia. J Clin Oncol. 1997;15(5):1824–30. View Summary + Annino L , Vegna M , Camera A . et al. Treatment of adult acute lym...
Integration of Phytotherapy with conventional treatment has been examined, which has provided positive results. Together, TCM and clinical pharmacology could achieve more than any of them could do separately.[17] Psychosocial Factors: A growing body of research is examining how psychosocial factors, suc...
OBJECTIVES: Our objective was to examine the effect of different fruits and their constituents on P-glycoprotein and organic anion transporting polypeptide... - 《Clinical Pharmacology & Therapeutics》 被引量: 938发表: 2002年 Incidence of Adverse Drug Events and Potential Adverse Drug Events OBJECTIVES...
Systemic effects of inhaled corticosteroids on growth and bone turnover in childhood asthma: a comparison of fluticasone with beclomethasone Eur Respir J, 13 (1999), pp. 87-94 View in ScopusGoogle Scholar 27. PJ Barnes, S Pedersen, WW Busse Efficacy and safety of inhaled corticosteroids Am J...