This review will focus on vaccine approaches using full Tat. The difficulty in reviewing all the vaccine approaches that have included Tat or parts of Tat with other HIV proteins is to determine if the effect observed is related to Tat. A good pharmaceutical practice should be to test each ac...
Cyclooxygenase (COX) and COX-2 inhibition, as well as minor lipoxygenase inhibition have also been noted for Echinacea extracts and specific alkylamides.13,104-107 This would potentially have an additive, or possibly synergic effect in the anti-inflammatory activity that the CB2R activation has ...
In detail, the plant-derived arbutin (β-d-glucoside of hydroquinone) was employed in synergic combination with the silane precursor [3-(2-aminoethylamino) propyl]trimethoxysilane (AEAPTMS) and paraformaldehyde for the production of the benzoxazine polymer resin (Figure 21a,b) applied by dip-...
On the other hand, ezetimibe co-administration with statins seems to promote a clear-cut synergic effect, resulting in an additional 15% to 25% reduction in serum LDL-C, regardless of the statin type and dose [126]. Tremblay et al. evaluated the effects of ezetimibe on the in vivo ...
in association with C1q macrophage production, led to the canonical complement cascade activation; (ii) C1s modified the tumor cell transcription program and phenotype and promoted their proliferation and survival; (iii) a complex synergic interaction between the C1q-producing tumor cells and T cells ...