Regarding updates on non-melanoma skin cancer, Rigel mentioned tirbanibulin ointment, a synthetic, antiproliferative agent that binds tubulin, inhibits tubulin polymerization and disrupts SRC signaling in actively dividing cells, for the treatment of actinic keratosis. In a clinical trial of tirbanibulin...
From a therapeutic perspective, antiplatelet or anticoagulant therapy is recommended for APS, but it remains to be established whether this treatment can reduce progression to clinically significant PH or reduce the occurrence of PH-related complications in patients with PSVD and isolated serum aPL posi...
Kangen water is one of many brand names for so-calledalkaline waterspromoted as a healthier form of water with significant anti-oxidant properties. It's generally presented as the result of an electrolysis process which separates ordinary water (H20) into two separate entities. One half of the ...
1. Introduction The hypomethylating agents (HMA) azacitidine (AZA) and decitabine (DEC) have been a mainstay of the treatment of myeloid neoplasms for almost two decades now. These two closely-related agents primarily act by epigenetic mechanisms, the disruption of which is central to the ...
It is common for patients with cancer to require some level of surgical procedure either as part of their disease management, for emergency treatment or in symptom control. This review aimed to evaluate the available evi- dence around surgical complications in patients receiving systemic anti-cancer...
At month 6, the treatment group had 62% fewer new AKs than did the placebo group (average per patient, 1.78 and 4.73, respectively), a statistically significant difference. For preventing AKs, 5-FU beats placebo for up to 3 years FCA violations may be predicated on the submission of claims...
Notably these rats were uninjured and had similar alpha diversity to uninjured, non-anxious-like rats, which is important since a diverse microbial diversity has been shown to be an indicator of FMT success for treatment of ulcerative colitis and Clostridium difficile infections [19,22]. We ...
Gene therapy is an encouraging alternative treatment for these respiratory diseases; however, more research is needed to ensure treatment safety and efficacy. Keywords: gene therapy; rare respiratory diseases; alpha-1-antitrypsin deficit; cystic fibrosis; primary ciliary dyskinesia 1. Introduction 1.1. ...
Treatment with specific SERT inhibitors leads to an increase of free 5-HT content, thus empowering 5-HT effects, not only in GIT but also in CNS [83]. 3.4. Serotonin Signalling and Physiological Functions It is well known that 5-HT has also been involved in very complex physiological ...
Since more than 161 million people worldwide suffer from visual impairment and thereof 37 million are blind, an adequate treatment is of high interest [74]. Generally, coronial blindness can be surgical treated by transplantation of the corona. As 90% of visually impaired people live in low- ...