The amyloid beta (Aβ) cascade hypothesis is the most prominent mechanistic description of the progression ofAlzheimer's Disease(AD). According to this hypothesis, the deposition of Aβ is an early salient event that precedes several events, including the formation ofneurofibrillary tangles(NFTs) in...
The first enzyme replacement therapy (ERT) for a lysosomal storage disorder (LSD) was approved in 1991 and we now have more than 25 years of experience of treating patients with type 1 Gaucher disease. Because of the remarkable success of this therapy, enormous effort and resource has gone ...
In the aerobic atmosphere currently prevailing at the Earth’s surface, the most stable form of carbon is its fully oxidised state, CO2. The atmosphere contains 2.6 x 1012tonnes of carbon as CO2which is in equilibrium with even larger amounts (1.3 x 1014tonnes) in solution in the rivers, ...
The Western blot test, also called immunoblotting, is a test for a specific protein within a protein mixture. The Western blot test is performed after gel-electrophoresis or an enzyme-linked immunosorbent assay (ELISA) test, and it uses antibodies to identify specific proteins. SDS-PAGE Sodium ...
· Zygomycota - This is a relatively small group made up of organisms that are referred to as saprobes. As such, they largely depend on decaying organic material as the source of energy. A few species, however, are parasitic in nature. Zygomycetes reproduce asexually and produce zygospores...
There is no doubt that the personalisation of medicine will help to get rid of the limitations and dilemmas of disease-based medicine. However, given the current approach to precision medicine, can a system of personalised medicine to deal with diseases more effectively be built? What i...
What is the process of protein synthesis also known as? What is a cofactor for an enzyme or other protein? Which protein is defective in the disease cystic fibrosis? What are fibrous proteins? Give three examples. What type of protein will help increase the probability of an enzyme interaction...
What is the importance of Prochlorococcus for life on Earth, both historically and in the present day? What is the importance of capsules and slime layers, and why are biofilms so important from a medical standpoint? Describe how the memory process is affected by Alzheimer's disease. How can...
What is Industrial Hygiene & How Does it Contribute to Safety at Work? - Learn More at Vector Solutions where we are making companies safer, smarter, and better.
Why is the etiology of a disease important? Why is it important to ask a patient if the mass is fixed? Why is that important to note? What could this mean? Discuss one specific event that occurs during the relaxation of a muscle fiber and why it is important. ...