The influence of the book on non-scientists is described. Future research in odonatology on aspects that have not been studied and others that need further investigations are discussed.Rassim KhelifaDepartment of Evolutionary Biology and Environmental StudiesUniversity of ZurichGunther Theischinger...
Biology of Sex Differences 2012, 3:24 http://www.bsd-journal.com/content/3/1/24 REVIEW Open Access Sex and gonadal hormones in mouse models of Alzheimer's disease: what is relevant to the human condition? Dena B Dubal*, Lauren Broestl and Kurtresha Worden Abstract Biologic sex and ...
Several DDR pathways are engaged in the processing of deprotected telomeres, including the classical and alternative non-homologous end joining (NHEJ) pathways and the homologous recombination pathway. Studies aimed at defining how functional telomeres suppress these pathways have been instrumental in shedd...
N-ras, derived from the neuroblastoma cells, is also a type of protein that belongs to the GTPase group of proteins. N-ras also helps in activating the signal transduction mechanism and the signal cascade belonging to the activation of the RASK pathway. Thus, the main function is to aid th...
Pentose Phosphate Pathway: The pentose phosphate pathway is one of the alternative metabolisms of glucose that occurs in the cytosol of a biological cell. This pathway is also known as hexose monophosphate shunt and helps maintain a lower glutathione concentration in the body. ...
Chemical formula is that of mibefradil. TTCCs and the RAF/RAS/MAPK pathway: A second positive feedback mechanism for cancer cell proliferation and survival? Of the above-mentioned possibilities, the existence of a TTCC–extracellular signal-regulated kinase (ERK) axis has been reported in ...
Oncogenic mutation of PIK3CA in small cell lung carcinoma: a potential therapeutic target pathway for chemotherapy-resistant lung cancer. Cancer Lett. 283, 203–211 (2009). CAS PubMed Google Scholar Cui, M. et al. PTEN is a potent suppressor of small cell lung cancer. Mol. Cancer Res. ...
However, as IL-6 signaling occurs through JAK/STAT-mediated transduction, this pathway has been suggested to play a possible role (Fig. 3). Constitutive activation of JAK1 in a mouse model leads indeed to the development of a SLE-like clinical picture, simultaneously characterized by the ...
It appears that dietary modification in rodents has limited translatable benefit for understanding and treating human obesity and diabetes. The purpose of this review is to investigate the reasons for this translational discrepancy. This paper also addresses future directions necessary to conduct ...
What are downstream pathways in biology? What are anabolic and catabolic pathways? What is the JAK-STAT pathway for cell signaling? How are signaling pathways turned off? What are the different forms of chemical signaling? What does phosphatidic acid do in cell signaling? What is amplification in...