Column 16. What Is the Actual Status of Radiotherapy (External Beam Radiotherapy and 131I MIBG Therapy)?Evidence is lacking for external beam radiotherapy for medullary carcinoma, and its significance remains unknown. A therapy using 131 I MIGB, which is a norepinephrine analogue, can be ...
Over 18 years, tumor progression was managed with 131I-MIBG (iodine-metaiodobenzylguanidine) and 177Lutetium-octreotate therapy. Currently, the patient is asymptomatic and presents sustained stable disease, despite the presence of lung, para-aortic lymph nodes and femoral metastases. Adequate ...
MIATCO MIATM MIAU MIAUG MIAVI MIAW MIAWS MIB MIB-II MIBA MIBank MIBARS MIBB MIBC MIBCI MIBDE MIBE MIBEL MIBERS MIBF MIBG MibGits MIBH MIBI MIBiol MIBK MiBKC MIBL MIBM MIBN MIBO MIBOM MIBOR MIBP MIBR MIBS MIBT MIBTEL ▼
Furthermore, the value of image parameters (also called “biomarkers”) is often sub-optimal due to physical and methodological limitations of the diagnostic methods employed: anatomical imaging, for example, may not detect or characterize a lesion because it is not manifested as a morphological alt...
Metaidobenzyleguanidine (MIBG) imaging was performed in 69% of patients, 91% of which were positive. Median time from surgery until recurrence was 36months (1–295months). Radiation therapy was the most common adjuvant treatment (44%) followed by Iobenguane I-131 (31%) and systemic therapy...
Furthermore, biological characteristics, including sensitivity to chemotherapy, might be lesion dependent because NSE immunohistochemistry in the primary lesion, uptake of [sup.123]I-MIBG in the primary lesion and metastatic sites, and MYCN amplification in the primary lesion and bone marrow aspirate we...
Metaidobenzyleguanidine (MIBG) imaging was performed in 69% of patients, 91% of which were positive. Median time from surgery until recurrence was 36months (1–295months). Radiation therapy was the most common adjuvant treatment (44%) followed by Iobenguane I-131 (31%) and systemic therapy...