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In breast cancer fatality is often due to the development of metastatic disease (MBC). Almost 30% of early breast cancer patients eventually develop MBC and in 90% of these multi-drug resistance (MDR) occurs. This could be attributed to the presence of breast cancer stem cells (BCSCs). ...
摘要: Despite the discovery of the tubercle bacillus more than a hundred years ago, and all the advances in our knowledge of the disease made since then, tuberculosis still remains one of the major health problems facing mankind, particularly in developing countries....
Metastatic cancer, for some but not all tumor types, is considered by many physicians and researchers to be an incurable disease, but many patients have a chronic course, living for a long time and leading functional, fulfilling lives. Treatment and prognosis for metastatic cancers are dependent ...
Using the SF-36 measure to compare the health impact of multiple sclerosis and Parkinson's disease with normal population health profiles To examine the relative impact of two chronic neurological disorders, multiple sclerosis and Parkinson's disease, by comparing patients' scores on the medi... A...
Abstract. Herceptin® (trastuzumab), an anti-HER2 monoclonal antibody, is the first oncogene-targeted therapy to be developed for the treatment of
Based on clinical characteristics, histology and metastatization phenomena, BC is a heterogeneous and complex disease with specific molecular subtypes (Afifi and Barrero, 2023). Different tumor phenotypes exist, characterized by a complex cellular origin, as well as a heterogeneous progression of the ...
Previous randomized controlled trials of adjuvant chemotherapy or chemoendocrine therapy in premenopausal women have estimated 5-year metastatic breast cancer (MBC) incidence at 6% to 12% [241,242]. However, this is likely an underestimate given patients who develop metastatic disease tend to be ...
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