The film is in pre-production stage and for Agarwal's other film Vasooli, Dutt had only shot for four days.Film Dutt was dropped fromSanjay Dutt's cameo in Emraan Hashmi-Vidya Balan-starrer Ghanchakkar was much publicised.The scrapping of the cameo was bound to make noise.Sanjay Dutt's...
Transcriptional Master Regulators of Hypertrophy The transcriptional networks which regulate hypertrophic growth have been intensively studied in experimental HF models. Notwithstanding that transcriptional control of cardiac growth is a highly complex process, a small number of key transcription factors represent...
but relapse and subsequent chemotherapy resistance is common. Increasing preclinical data suggest that autophagy is active in leukemia as a means of promoting cell survival in response to chemotherapy. We propose coupling autophagy inhibition strategies with current cytotoxic chemotherapy and discuss synergist...
Fluorescence correlation spectroscopy is used as a quantitative method to understand the binding and exchange behaviour of proteins on the surfaces of nanoparticles. This is a preview of subscription content, access via your institution Access options Subscribe to this journal Receive 12 print issues ...
Hormone transporters are crucial for plant hormone action, which is underlined by severe developmental and physiological impacts caused by their loss-of-function mutations. Here, we summarize recent knowledge on the individual roles of plant hormone tran
2 Validation of the microarray data by performance of quantitative real-time PCR (qPCR). Eight genes, including (a) rpf2, (b) spon1b, (c) tspan7b, (d) rps27.2, (e) stra13, (f) rtn4ip1, (g) U1, and (h) slc29a1a were subjected to qPCR using the primers listed in ...
In photosynthetic organisms, light energy is absorbed by a complex network of chromophores embedded in light-harvesting antenna complexes. In photosystem II (PSII), the excitation energy from the antenna is transferred very efficiently to an active reaction center (RC) (i.e., with oxidized primary...
Recent years have seen so-called natural killer T (NKT) cells emerge as important regulators of the immune response. The existence of NKT-cell subsets, and other types of T cell that resemble NKT cells, is an ongoing source of confusion in the literature. This perspective article seeks to ...
Large-scale cancer genomics, proteomics and RNA-sequencing efforts are currently mapping in fine detail the genetic and biochemical alterations that occur in cancer. However, it is becoming clear that it is difficult to integrate and interpret these data and to translate them into treatments. This ...
in the 1970s [8]. They are synthesized based on four polypeptide chains, encoded by thePDGFA,PDGFB,PDGFC, andPDGFDgenes. ThePDGFAgene is located within chromosome 7 (7p22) [9] and is highly expressed in most human tissues [10]. The data available so far indicate the significant role...