Frontotemporal dementia (FTD) is the clinical manifestation of progressive nerve cell loss in the frontal and anterior temporal lobes. It represents the second most frequent form of early-onset dementia. The two major types of FTD are determined by the localisation of the underlying pathology. The...
Pre-operative localisation of the target struc- tures can be performed either directly from pre-operative MRI or through intraoperative recordings using micro- electrodes (MER), to identify characteristic activity of individual STN or pallidal neurons. There is an ongoing debate as to the advantages...
Previous research that explored sound source localisation (but not using MMN) has generally found that tinnitus interferes with this ability especially at a higher frequency [86], but only in certain sound types that included pure tones [87]. However, this may be in part due to effects of ...
Besides, to support the localisation of ICD systems, classification standards are updated regularly (e.g., usually every few months in Public Health Scotland6). Automated clinical coding needs to work with dynamic and complex classification systems. (3) The social-technical issues with automated ...
In these ways, for a non-invasive technique, MEG best combines high temporal resolution and improves source localisation within the human brain. What exactly do those tiny magnetic fields reflect about brain activity? When a neuron receives communication from a neighbour, an excitatory or inhibitory...
The localisation of the protein has important implications for the likely route of escape. Yet another proapoptotic protein seems to reside in mitochondria, but here the functional significance of the mitochondrial localisation is not yet clear. SM-20 is a Cell Death and Differentiation protein ...
CSF rhinorrhea is observed in head trauma and can be easily distinguished by a simple glucose dipstick test[76]. Throat clearing, dysphonia, and vocal fatigue can be observed in many patients with postviral vagal neuropathy[77]. However, a detailed discussion of these symptoms is out of the ...
[56,57,58]. Co-localisation has been particularly beneficial for oncological applications of SPECT, where for example, CT can help determine whether bone lesions are cancerous or degenerative in nature, and also with radiopharmaceuticals such as mIBG, where the anatomical information available in ...
Yet, alternative methods such as Bayesian colocalisation allow the overlap of GWAS hits and QTL while mitigating the confounding effects of LD (Schilder and Raj, 2022). Moreover, along with the simultaneous spur in GWAS, genome-wide functional studies have shown that the risk loci identified ...
Recently, the discussion regarding the consequences of cutting the corpus callosum (“split-brain”) has regained momentum (Corballis, Corballis,