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Clinical coding is the task of transforming medical information in a patient’s health records into structured codes so that they can be used for statistical analysis. This is a cognitive and time-consuming task that follows a standard process in order t
What happens that makes the loss of function ± signalled in the brain by a loss of consciousness ± irreversible? Key questions in apoptosis research must now be: how is cyt c release regulated? How is it initiated? Indeed, how is it prevented? Are there multiple routes and mechanisms ...
The brain consists of some 100 billion nerve cells (give or take a few bil- lion). Each cell is connected to thousands of other nerve cells in an astonishingly complex network. In scientific terms, the brain is sometimes called 'the final frontier,' because its function is still not ...
The EEG originates everywhere in the cerebral cortex...In the EEG a fundamental function of the human cerebrum intimately connected with the psychophysical processes becomes visible manifest." (see here for a history of Hans Berger and the EEG) Decades later, the correctness of his position is ...
The anal wink in response to cough or sniff is a significant clinical sign during a neurological examination. It could be elicited by asking the patient to voluntarily cough or sniff while observing the anus. This reflex is not affected by transection of the spinal cord while being lost in ca...
this progress in technologies and instrumentation is complemented by advances in relevant acquisition and image-processing protocols and improved data analysis. To this end, we should accept diagnostic images as “data”, and – through the wider adoption of advanced analysis, including machine learning...
Yet, alternative methods such as Bayesian colocalisation allow the overlap of GWAS hits and QTL while mitigating the confounding effects of LD (Schilder and Raj, 2022). Moreover, along with the simultaneous spur in GWAS, genome-wide functional studies have shown that the risk loci identified ...
Advanced-stage PD is characterized by insufficient motor control including motor fluctuations, such as dyskinesia and OFF periods, despite optimized oral dopaminergic medication (Soileau et al.2022). In everyday clinical routine, the 1-2-5 criteria can be used for the identification of advanced PD...
Numbing or removing the (nerve)tissues b or organs, or knocking out genes, thought to form the basis of a magnetic sensory system allows the localisation of body parts involved (e.g. [7] or [8]). Direct alteration of the perceivable magnetic field can be achieved by attaching magnets ...