KEGG pathways analysis also showed that the most significant enriched pathways are related to immune system functions, corrobor- ating GO analysis (data not shown). As the contribution of immune system components to muscular dystrophies pathogenesis is well known, we removed this category and ...
Pathway abundances are calculated as the harmonic mean of the key reaction abundances in a sample (the distinction of "key" reactions is for structured pathways like MetaCyc, which have both optional and key reactions). There are some other subtleties as well, such as gap filling by default (...
Pathway analysis was performed based on surfaceome data. Enriched growth-related pathways were further evaluated using mRNA expression data. Created with BioRender.com. b Identified surface receptors of the PI3K/AKT pathway in the surfaceome (left) and their annotation in the KEGG PI3K/AKT pathway...
To this end, however, we first need a comprehensive conception of what constitutes achemistry-likereaction network. The different representations used in the literature highlight the fact that it is far from obvious which graphs or hypergraphs properly describechemicalRNs among a possibly much larger ...
The results of the KEGG analysis revealed that the potential signaling pathways targeted in COVID-19 treatment with MXSGD were mainly enriched in the immune system and viral infection. An in vitro study also found that MXSGD effectively inhibited IL-6-stimulated JAK–STAT activation and inhibited...
Gastric cancer (GC) is one of the most common malignancies causing death worldwide, and Helicobacter pylori is a powerful inducer of precancerous lesions and GC. The oral microbiota is a complex ecosystem and is responsible for maintaining homeostasis, m
TPL is included to illustrate its potential interacting partners in network. The network was generated using IntAct [24]. Figure 6. Assessment of potential TFs with physical association with pMYB98 or putative TFs binding to it (84 in total). (a) KEGG pathway analysis of TFs shows 9 ...
A gene or a miRNA can be specified in the search field and in all cases a KEGG description can be included and the species can be chosen. This procedure on the web is the same for both the microT-CDS and microT v4 algorithms. However, as expected, the results are presented differently...
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Genes containing DMRs and DEGs and were uploaded to the DAVID webserver (https://david.ncifcrf.gov/) for functional enrichment analysis for gene ontology (GO) terms involving molecular function, biological processes and the Kyoto encyclopedia of genes and genomes (KEGG) pathway (Benjamin-corrected...