The FDA warning included sitagliptin, saxagliptin, linagliptin, and alogliptin, noting the potential for severe and disabling joint pain. In addition, the FDA added a new Warning and Precaution about this risk to the labels of all medications in this drug class. Editors' Recommendations DPP-4 Inh...
in fact, incorrect. Today’s type 2 diabetes is “not your mother’s type 2 diabetes,” that is, our modern understanding of dysglycemia is a departure from old tenets. A correct understanding of beta cell function
at relatively lower or even normal levels; this combination is often referred to as unfavorable discordance. Unlike the general population, in this setting, where the population (i.e. insulin resistance, obesity, prediabetes, metabolic syndrome, high TG levels, low HDL-C levels, T2DM) is enrich...
Increased rates of hospitalization for heart failure were seen with both saxagliptin and alogliptin, and this has led to a class warning for all dipeptidyl peptidase-4 inhibitors. Summary Future studies should have a standardized definition of "hospitalization for heart failure," should consider ...
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Development and Validation of an HPLC Method for Determination of Antidiabetic Drug Alogliptin Benzoate in Bulk and Tablets For this aim, acetic acid-ammonium acetate buffer (pH 5-7.5) has been recently used as a modifier for the purification and separation of many azo dyes by RP-HPLC [19,20...