1 Following licensure, safety remains of prime concern; ongoing surveillance evaluates vaccine safety in large populations under real-world settings. Fundamental to this process is the contribution of the Brighton Collaboration, a network whose aim is to establish clear case definitions for individual ...
STING is a vital protein in the innate immune response. Learn how Bio-Techne's STING Antibodies can be used in your cancer and immunology research.
Immunoglobulins (Ig) are the immune factors most studied in human milk. Dimeric IgA or pentameric IgM confer the infant immune protection against antigens to which the maternal mucosal-associated lymphoid tissues (MALTs) have been exposed and, therefore, to which the baby ...
Even if surgery is successful in removing the primary tumor, there is often residual disease, either as dormant or active tumor cells and micrometastases. The myriad of immunological processes that can synergistically promote metastases in the immediate perioperative period emphasizes the importance of ...
The Biological Impact of Oxidative Metabolism in Trypanosomatid Parasites: What Is the Perfect Balance Between Reactive Species Production and Antioxidant Defenses?Chapter First Online: 27 October 2019 pp 127–173 Cite this chapter Oxidative Stress in Microbial Diseases ...
Seminars in ImmunologyMatthias, P. 1998. Lymphoid-specific transcription mediated by the conserved octamer site: who is doing what? Semin. Immunol. 10:155.Lymphoid-specific transcription mediated by the conserved octamer site: who is doing what? Semin. Immunol - Matthias - 1998 () Citation ...
Recent years have seen so-called natural killer T (NKT) cells emerge as important regulators of the immune response. The existence of NKT-cell subsets, and other types of T cell that resemble NKT cells, is an ongoing source of confusion in the literature
IDO1, a monomeric heme-containing enzyme, is one of the three enzymes that catalyze the first and rate-limiting step in the kynurenine pathway (KP), leading to the degradation of the essential amino acid tryptophan (TRP) and generation of kynurenine (KYN) and other downstream metabolites, in...
In other words, offspring develop in a prenatal environment that is shaped by lifetime exposures to environmental conditions, and at birth, neonates are colonized by microbiota shaped by the same factors. Innovative approaches and methods are now needed to disentangle the complex interactions between ...
Interestingly, CD4+ T cell polarization into Tfh happens with IFN exposure at early stages of the infection, while exposure at delayed stages promotes differentiation into Th1 cells [26]. As mentioned above, reduced levels of IFN-α production by dendritic cells is a feature found in both T1DM...