Disorders of keratinization encompass a wide variety of monogenic skin diseases characterized by inheritable disturbances in the differentiation of epidermal keratinocytes leading to hyperkeratosis and/or epidermal fragility. Over the last decade, many new etiologies have been found for these diseases, but...
These conditions cause excessive proliferation of keratinocytes at the nail bed’s distal end and buildup of debris toward the proximal end of the nail, also known as “subungual hyperkeratosis.” (10) Psoriasis of the nail is known to occur as a dysregulated immunological response of the ...
Retinoids aid in the normalization of hyperkeratinization, which means they help your skin slough off (ordesquamate) dead skin cells at a more normal rate so the dead skin cells don't bind together and clog your pores. This is important because if your hair follicles are clogged, you getker...
Decreasing theC. acnesquantity is no longer key to clearing acne, but rebalancing its distribution between acneic and non-acneic strains is. The recovery of acnebiome™ (microbiome related to acne) homeostasis by Dendriclear™ decreases skin bacterial...
Smoking: In my experience, smokers commonly see milia appear around their eyes. It could be that smoke is blown upwards into the eye area, causing keratinization of the skin. How to Prevent Milia To prevent milia from forming, you want to exfoliate regularly. This will prevent dead skin cell...