MSC-100-IV for acute graft versus host disease MPC-300-IV for biologic refractory rheumatoid arthritis and diabetic nephropathy I hope this gives relief to those suffering, and in a sense begs the question “why is the FDA, medical industry, clinical trial industry, not pursuing this new fie...
Mutations of Foxp3 gene can hinder the development of Tregs and lead to a fatal multi-organ autoimmune disease which is called X-linked polyendocrinopathy enteropathy with immune dysregulation syndrome [30]. In addition, CD4+ T cells can also transiently express Foxp3 upon activation [31]. ...
The potential causes of neurogenic oropharyngeal dysphagia in cases in which the underlying neurologic disorder is not readily apparent are discussed. The most common basis for unexplained neurogenic dysphagia may be cerebrovascular disease in the form of either confluent periventricular infacts or small,...
Background The concept of core-microbiome in health is useful for investigating the possible role of the oral microbiome in autoimmune disease, such as Rheumatoid Arthritis, Spondyloarthritis, Sjogren Syndrome or Systemic Sclerosis (SSc), whose pathogenesis has not been fully understood. Environmental ...
In recent years, the role of diet in the pathogenesis of inflammatory bowel disease (IBD) has gained great interest within the scientific community. Eating habits from industrialised countries (the so-called western diet or WD) have been associated with a higher incidence of IBD in observational ...
While there is some evidence to suggest that strains from an infant’s own mother may be particularly compatible with the infant’s gut [86], some mothers may harbor a suboptimal microbiota e.g. due to antibiotic use or disease. Further research is needed on FMT to infants. Probiotics can...
(Crohn’s disease and ulcerative colitis), autoimmune disorders (lupus, rheumatoid arthritis, and vasculitis), and lung diseases like asthma. Moreover, there is a slight risk of having a CRP test as it may cause slight pain or bruising at the spot where the needle is put in. However, ...
With heart disease, CRP levels tend to be modestly elevated and will gradually increase as the disease progresses. A test called a high-sensitivity CRP (hs-CRP) test can be used in people with risk factors for heart disease to decide whether treatment is needed.3 ...
Thyroid antibodies are a marker of autoimmune thyroid disease. They let us know that the immune system is destroying thyroid tissue, which can cause a release of hormones into the bloodstream. This can lead to transient (or temporary) hyperthyroidism, as well as mood-related symptoms such as an...
(CTLA-4) on the surface of Treg cells, and there is a linear correlation between them [28,29]. Mutations of Foxp3 gene can hinder the development of Tregs and lead to a fatal multi-organ autoimmune disease which is called X-linked polyendocrinopathy enteropathy with immune dysregulation ...