hnRNPsmRNA decaymRNA translationp53post-transcriptional regulationribosomal proteinsRNA binding proteinsGenotoxic stress leads to DNA damage which can be detrimental to the cell. A well-orchestrated cellular response is mounted to manage and repair the genotoxic stress-induced DNA damage. Our understanding...
prior to deduplication. This is done by assessing the distance between the individual sequences and the proposed parental sequence. Deduplication is then based on the parental UMI sequence and also removes reads with slight alterations in the UMI sequence (e.g., caused by nucleotide mis-...
A total of six gene fusions not identified in the cytogenetic workup were identified including KMT2A-MLLT4, KMT2A-MLLT3, HNRNPH1-ERG, NUP98-NSD1, CBFA2T3-GLIS2, and SEPT6-KMT2A. CNVs were identified in samples from eight patients with ZEB2 as the most commonly impacted gene (n = 4)...