For her, the approval of these two algorithms offers “a glimpse of where we may be going in the future and how the electronic medical records may be harnessed in a meaningful way to triage and connect patients who will benefit from it.” Further validation, though, is needed in additionall...
HFrEF population investigated in the PARADIGM HF study (RR 0.79: CI 0.71–0.89) [20], highlighting that a normal LVEF does not address the absence of systolic dysfunction and that the female gender reacts differently to medical therapy, probably due to heart reverse remodeling capability [21,22...
Epidemiologically, the lifetime risk of developing HF is approximately the same for both sexes. Women represent approximately 25% of patients diagnosed with HF with reduced ejection fraction (HFrEF). In contrast, they make up about 50% of those affected by HF with preserved ejection fraction (HFp...
Heidenreich and colleagues estimated that the total medical costs of HF in the US will increase from $31 billion in 2012 to at least $70 billion in 2030 [3]. Thus, it is not only important to find new therapeutic approaches, but also to diagnose affected individuals early and monitor ...
Moreover, several metanalyses that included the DANISH trial showed that the reduction in all-cause mortality in patients who benefited from an ICD is identical in those with HFrEF due to ischemic and non-ischemic causes (HR–0.76) [21]. Beggs et al. in their 2017 analysis, which examined...