It is sometimes called the HER2/neu receptor and helps in the growth, division, and repair of breast cells. Some breast cancer cells may have a genetic mutation called HER2 gene amplification, which may cause the overexpression of HER2 receptors. This makes cancer cells multiply rapidly. ...
ER+ and HER2/neu-positive subtype ER+ and HER2/neu-negative subtype Basal-like breast cancer Breast cancer diagnosis A diagnostic delay, or the time between when you first notice symptoms and when you are diagnosed with breast cancer, determines how quickly you’re treated. The longer it tak...
strategies for patients with human epidermal growth factor receptor 2 (HER2)-positive disease and triple-negative breast cancer (TNBC) who have residual disease after preoperative systemic therapy.#There has been a shift towards neoadjuvant systemic therapy for selected patients with HER2-positive and ...
Breast cancer and pregnancy: how safe is trastuzumab? A 29-year-old woman was diagnosed with lymph-node-positive, steroid-hormone-receptor-negative and HER2/neu-positive breast cancer. She underwent surgery fo... HA Azim,FA Peccatori,SJ Liptrott,... - 《Nature Reviews Clinical Oncology》 被...
HER2 Dictionary, Encyclopedia and Thesaurus - The Free Dictionary13,628,821,892visits served TheFreeDictionary Google ? Keyboard Word / Article Starts with Ends with Text EnglishEspañolDeutschFrançaisItalianoالعربية中文简体PolskiPortuguêsNederlandsNorskΕλληνικήРусск...
Targeting HER2/neu-positive breast cancer Positive results from five recent large randomized trials of adjuvant trastuzumab have shown how molecularly targeted therapy can dramatically improve clinical outcome. HER2/neu is an oncogene in the EGFR family that is over-...
What is triple-negative breast cancer? Triple-negative (ER-negative, PR-negative, HER2/neu not overexpressed) breast cancer has distinct clinical and pathologic features, and is a clinical probl... WJ Irvin,LA Carey - 《European Journal of Cancer》 被引量: 387发表: 2008年 Axillary staging of...
That means 17.6% of triple negative breast cancers transform to Her2 positive status. Brufsky et al4 have shown that almost 33% of Her2 positive breast cancers have had CNS metastasis. Triple negative breast cancers have also shown increased vascularity on MRI scans of the breast,6,9 ...
What do all cancer cells have in common? How common is breast cancer metastasis? What type of cell communication breakdown causes breast cancer? What is HER2 NEU breast cancer? What causes HER2 positive breast cancer? Is breast cancer a genetic disease? What causes triple negative breast cancer...
Weekly herceptin with navelbine in chemonaïve patients with HER2 positive metastatic breast cancer: A phase II multicenter trial (abstract 429). Breast Cancer Res Treat 2001;69:284. 42. O’Shaughnessy JA, Vukelja S, Marsland T, Kimmel G, Ratnam S, Pippen J: Gemcitabine and trastuzamab ...