However, despite the tremendous progress attained, disease progression, even with trastuzumab and lapatinib treatment, is inevitable in metastatic breast cancer. Thus, research efforts have focused on finding alternative therapies to trastuzumab and lapatinib for the treatment of Her2-positive breast cancer...
It is sometimes called the HER2/neu receptor and helps in the growth, division, and repair of breast cells. Some breast cancer cells may have a genetic mutation called HER2 gene amplification, which may cause the overexpression of HER2 receptors. This makes cancer cells multiply rapidly. ...
What is HER2 NEU breast cancer? What is residual breast cancer? What is a malignant tumor in the breast? What oncogenes are associated with breast cancer? What is an oncotype test for breast cancer? What does stage 1b breast cancer mean?
ER+ and HER2/neu-positive subtype ER+ and HER2/neu-negative subtype Basal-like breast cancer Breast cancer diagnosis A diagnostic delay, or the time between when you first notice symptoms and when you are diagnosed with breast cancer, determines how quickly you’re treated. The longer it takes...
HER2/neu in systemic therapy for women with breast cancer: a systematic review Amplification and/or overexpression of the HER2/neu gene is associated with a poor prognosis in breast cancer. Many studies have suggested that this gene m... B Dhesy-Thind,KI Pritchard,H Messersmith,... - 《Br...
By the use of gene expression profiles, 4 breast cancer subtypes with different prognoses have been identified: 2 ER-negative subtypes: basal-like (BL) and human epidermal growth factor receptor 2 (HER2)-positive, and 2 ER-positive subtypes: luminal A and luminal B. 1-4 Breast cancers are...
HER2 Dictionary, Encyclopedia and Thesaurus - The Free Dictionary13,628,821,892visits served TheFreeDictionary Google ? Keyboard Word / Article Starts with Ends with Text EnglishEspañolDeutschFrançaisItalianoالعربية中文简体PolskiPortuguêsNederlandsNorskΕλληνικήРусск...
Targeting HER2/neu-positive breast cancer Positive results from five recent large randomized trials of adjuvant trastuzumab have shown how molecularly targeted therapy can dramatically improve clinical outcome. HER2/neu is an oncogene in the EGFR family that is over-...
Immunostudies for cytokeratin (CK) 7, CK20, estrogen receptor, progesterone receptor, HER2 NEU and thyroid transcription factor-1 were negative, indicating that breast, lung, pancreatic and biliary tree metastases were unlikely. Immunoperoxidase studies were positive for CK5/6, epithelial membrane ...
HER2: Abbreviation forhuman epidermal growth factor receptor 2. HER2 is a transmembrane tyrosine kinase receptor and is expressed by, and involved in the growth of, some cancer cells. What does q2h mean in medical terms? q.2.h., q2h.every 2 hours. ...