Triple-negative (ER-negative, PR-negative, HER2/neu not overexpressed) breast cancer has distinct clinical and pathologic features, and is a clinical problem because of its relatively poor prognosis, aggressive behaviour and lack of targeted therapies, leaving chemotherapy as the mainstay of treatment...
Looking for online definition of Positive/Negative or what Positive/Negative stands for? Positive/Negative is listed in the World's most authoritative dictionary of abbreviations and acronyms
A negative genetic test means that a breast cancer gene mutation was not identified. If other genetic testing has identified a mutation in your family, a negative test means you do not have the specific mutation. Therefore, your risk of cancer is the same as someone in the general population...
Food and Drug Administration (FDA) approved everolimus in combination with the steroidal aromatase inhibitor, exemestane, for the treatment of postmenopausal women with advanced hormone receptor-positive, HER2-negative breast cancer, who experience recurrence or progression following treatment with a non-...
What is triple negative breast cancer? Triple negative breast cancer (TNBC) means that the cancer cells do not have estrogen (ER) and progesterone (PR) on their surface, and they do not over-express the HER2 protein as well (HER2−). In contrast to TNBC, triple positive breast cancer ...
strategies for patients with human epidermal growth factor receptor 2 (HER2)-positive disease and triple-negative breast cancer (TNBC) who have residual disease after preoperative systemic therapy.#There has been a shift towards neoadjuvant systemic therapy for selected patients with HER2-positive and ...
HER-positive tumors: Some breast cancer cells have high levels of a protein called HER2. If you are HER2-positive, you have the higher number of HER2 levels, your cancer may grow and spread faster than someone who is HER2-negative. But, if caught early enough, HER2-positive cancers often...
What is breast cancer?Breast cancer develops when cells in the breast grow out of control. Several types of breast cancer can develop, depending on which cells turn into cancer. Most breast cancers start in the tissue or ducts of the breast.What increases my risk for breast cancer?
Triple Negative and HER-2 Negative Breast Cancer A subset of women diagnosed with breast cancer will be told that their tumor is triple negative, which means that the cells within the tumor lack receptors on their surface that respond to human epidermal growth factor receptor 2 (HER-2) as we...
Is Orserdu Right for Me? Orserdu may be the right choice for you if: You are a woman after menopause or an adult man with ER-positive, HER2-negative breast cancer. Your cancer is advanced or has spread to other parts of your body (metastatic). You have ESR1 gene changes confirmed...